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- [2] Potent and selective RHO kinase inhibitors: Hit to lead accountABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238Prokopowicz, Anthony S., IIIWu, FrankCywin, Charles L.Snow, Roger J.Hickey, Eugene R.Kashem, Mohammed A.Shih, Cheng-KongKerr, SteveJakes, Scott
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- [5] Discovery and Hit to Lead Optimization of Macrocyclic Peptides as Novel Tropomyosin Receptor Kinase A AntagonistsJOURNAL OF MEDICINAL CHEMISTRY, 2024, 67 (13) : 11197 - 11208Yamada, ToruMihara, KousukeUeda, TaichiYamauchi, DaisukeShimizu, MasayaAndo, AzusaMayumi, KeiNakata, ZenzaburoMikamiyama, Hidenori
- [6] Discovery and SAR of novel heteroarylphenyl aniline derivatives as Rho kinase inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242Watanabe, JunkoTerasawa, TakeshiSawada, KouzoImamura, YoshimasaFukudome, HirokiMaeda, JunTakeshita, NobuakiTakeuchi, MakotoOhta, Mitsuaki
- [7] Discovery and hit-to-lead optimization of novel allosteric glucokinase activatorsBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (18) : 5417 - 5422Lang, MartinSeifert, Markus H. -J.Wolf, Kristina K.Aschenbrenner, AndreaBaumgartner, RolandWieber, TanjaTrentinaglia, ViolaBlisse, MarcusTajima, NobumitsuYamashita, TokuyukiVitt, DanielNoda, Hitoshi
- [8] Substituted 2-arylbenzothiazoles as kinase inhibitors: Hit-to-lead optimizationBIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (18) : 6728 - 6737Tasler, StefanMueller, OliverWieber, TanjaHerz, ThomasPegoraro, StefanoSaeb, WaelLang, MartinKrauss, RolfTotzke, FrankZirrgiebel, UteEhlert, Jan E.Kubbutat, Michael H. G.Schaechtele, Christoph
- [9] Small molecule inhibitors of Mdm2 as novel cancer therapeutics: From hit-to-lead generation to lead optimizationABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2699 - U2700Kim, KLiu, EMischke, SGSchutt, AVassilev, LTWang, BB
- [10] Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase InhibitorsJOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (05) : 2474 - 2478Li, RongshiMartin, Mathew P.Liu, YanWang, BinglinPatel, Ronil A.Zhu, Jin-YiSun, NanPireddu, RobertaLawrence, Nicholas J.Li, JiannongHaura, Eric B.Sung, Shen-ShuGuida, Wayne C.Schonbrunn, ErnstSebti, Said M.