Is Human Saliva an Indicator of the Adverse Health Effects of Using Mobile Phones?

被引:28
作者
Hamzany, Yaniv [1 ,2 ]
Feinmesser, Raphael [1 ,2 ]
Shpitzer, Thomas [1 ,2 ]
Mizrachi, Aviram [1 ,2 ]
Hilly, Ohad [1 ,2 ]
Hod, Roy [1 ,2 ]
Bahar, Gideon [1 ,2 ]
Otradnov, Irina [3 ]
Gavish, Moshe [3 ]
Nagler, Rafael M. [3 ,4 ,5 ]
机构
[1] Dept Otorhinolaryngol, Petah Tiqwa, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Rabin Med Ctr, IL-69978 Tel Aviv, Israel
[3] Technion Israel Inst Technol, Rappaport Fac Med, Rambam Med Ctr, Dept Mol Pharmacol, IL-31096 Haifa, Israel
[4] Technion Israel Inst Technol, Rappaport Fac Med, Dept Mol Pharmacol, Oral Biochem Lab, IL-31096 Haifa, Israel
[5] Rambam Med Ctr, Dept Oral & Maxillofacial Surg, Haifa, Israel
关键词
OXIDATIVE STRESS PARAMETERS;
D O I
10.1089/ars.2012.4751
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Increasing use of mobile phones creates growing concerns regarding harmful effects of radiofrequency nonionizing electromagnetic radiation on human tissues located close to the ear, where phones are commonly held for long periods of time. We studied 20 subjects in the mobile-phone group who had a mean duration of mobile phone use of 12.5 years (range 8-15) and a mean time use of 29.6 h per month (range 8-100). Deaf individuals served as controls. We compared salivary outcomes (secretion, oxidative damage indices, flow rate, and composition) between mobile phone users and nonusers. We report a significant increase in all salivary oxidative stress indices studied in mobile phone users. Salivary flow, total protein, albumin, and amylase activity were decreased in mobile phone users. These observations lead to the hypothesis that the use of mobile phones may cause oxidative stress and modify salivary function. Antioxid. Redox Signal. 18, 622-627.
引用
收藏
页码:622 / 627
页数:6
相关论文
共 9 条
[1]   Effects of Exposure to GSM Mobile Phone Base Station Signals on Salivary Cortisol, Alpha-Amylase, and Immunoglobulin A [J].
Augner, Christoph ;
Hacker, Gerhard W. ;
Oberfeld, Gerd ;
Florian, Matthias ;
Hitzl, Wolfgang ;
Hutter, Joerg ;
Pauser, Gernot .
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2010, 23 (03) :199-207
[2]   Effects of a 900-MHz Electromagnetic Field on Oxidative Stress Parameters in Rat Lymphoid Organs, Polymorphonuclear Leukocytes and Plasma [J].
Aydin, Birsen ;
Akar, Aysegul .
ARCHIVES OF MEDICAL RESEARCH, 2011, 42 (04) :261-267
[3]   Effects of third generation mobile phone-emitted electromagnetic radiation on oxidative stress parameters in eye tissue and blood of rats [J].
Demirel, Soner ;
Doganay, Selim ;
Turkoz, Yusuf ;
Dogan, Zumrut ;
Turan, Bahadir ;
Firat, Penpe Gul Bozgul .
CUTANEOUS AND OCULAR TOXICOLOGY, 2012, 31 (02) :89-94
[4]   The influence of handheld mobile phones on human parotid gland secretion [J].
Goldwein, O. ;
Aframian, D. J. .
ORAL DISEASES, 2010, 16 (02) :146-150
[5]  
JOHNSON D A, 1987, P135
[6]   Potential health risks of radiofrequency fields from wireless telecommunication devices [J].
Krewski, D ;
Byus, CV ;
Glickman, BW ;
Lotz, WG ;
Mandeville, R ;
McBride, ML ;
Prato, FS ;
Weaver, DF .
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS, 2001, 4 (01) :1-143
[7]   Characterization of the differentiated antioxidant profile of human saliva [J].
Nagler, RM ;
Klein, I ;
Zarzhevsky, N ;
Drigues, N ;
Reznick, AZ .
FREE RADICAL BIOLOGY AND MEDICINE, 2002, 32 (03) :268-277
[8]   Cellular phone use and risk of benign and malignant parotid gland tumors - A nationwide case-control study [J].
Sadetzki, Siegal ;
Chetrit, Angela ;
Jarus-Hakak, Avital ;
Cardis, Elisabeth ;
Deutch, Yonit ;
Duvdevani, Shay ;
Zultan, Ahuva ;
Novikov, Ilya ;
Freedman, Laurence ;
Wolf, Michael .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2008, 167 (04) :457-467
[9]   Relationship of flow rate, uric acid, peroxidase, and superoxide dismutase activity levels with complications in diabetic patients: Can saliva be used to diagnose diabetes? [J].
Zloczower, Moshe ;
Reznick, Abraham Z. ;
Zouby, Rula Obeid ;
Nagler, Rafael M. .
ANTIOXIDANTS & REDOX SIGNALING, 2007, 9 (06) :765-773