Pesticide residues in honey and their potential reproductive toxicity

Honey is the sweet natural substance produced by honeybees. It may be contaminated with pesticide residues due to its intensive use. Almost no reviews have addressed pesticide residues in honey, calculated a hazard index or discussed their potential reproductive toxicity. The focus of this article is primarily to summarize advances in research related to pesticide residues, estimate daily intake of pesticide residues from consuming honey only and discuss the potential reproductive toxicity associated with those residues. The results showed that 92 pesticide residues were found in honey samples from 27 countries. Six residues belong to class IA toxicity, eight residues belong to class IB toxicity, 42 residues belong to class II, 35 residues belong to class III and one residue belong to class IV toxicity. The calculated hazard indices (HIs) suggest high potential health risk by consuming honey. In addition, residues found in honey are known to impair semen quality among exposed individuals and experimental animal models. In conclusion, consumption of honey as one of many food items contaminated with pesticide residues may induce male and female reproductive toxicity in consumers. (C) 2020 Elsevier B.V. All rights reserved.