Successful Management of a Child With Drug-induced Necrotizing Pancreatitis During Acute Lymphoblastic Leukemia Therapy: A Case Report

被引：4

作者：

Plotka, Anna ^{[1
]}

Wziatek, Agnieszka ^{[2
]}

Wachowiak, Jacek ^{[2
]}

Derwich, Katarzyna ^{[2
]}

机构：

[1] Med Fac I, Dept Pediat Oncol Hematol & Transplantol, Students Sci Circle, Os Lecha 15-59, PL-61293 Poznan, Poland

[2] Poznan Univ Med Sci, Dept Pediat Oncol Hematol & Transplantol, Poznan, Poland

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2019年 / 41卷 / 02期

关键词：

children acute pancreatitis; drug-induced pancreatitis; pegaspargase; pediatric oncology; acute lymphoblastic leukemia; ASPARAGINASE-ASSOCIATED PANCREATITIS; OCTREOTIDE;

D O I：

10.1097/MPH.0000000000001181

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Acute pancreatitis in children acute lymphoblastic leukemia is commonly caused by drugs, for example, l-Asparaginase, pegapargase, steroids. The incidence of this complication is estimated at 6.7% to 18%. Although the majority of drug-induced acute pancreatitis cases are mild, severe cases can rarely occur. This work presents a case of successful management of a child with drug-induced necrotizing pancreatitis during acute lymphoblastic leukemia therapy. This case illustrates that comprehensive care and immediate intensive treatment can rescue patient despite poor prognosis. Administration of octreotide may serve a role in limiting the severity of the disease.

引用

页码：E125 / E128

页数：4

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