Large-scale chromatin structure and function

被引:98
作者
Belmont, AS [1 ]
Dietzel, S [1 ]
Nye, AC [1 ]
Strukov, YG [1 ]
Tumbar, T [1 ]
机构
[1] Univ Illinois, Dept Cell & Struct Biol, Urbana, IL 61801 USA
关键词
D O I
10.1016/S0955-0674(99)80041-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Recent results in living cells have now established the existence of levels of chromatin folding above the 30 nm fiber within interphase chromosomes. We discuss the potential functional impact of this large-scale chromatin organization, including its possible role in regulating gene expression.
引用
收藏
页码:307 / 311
页数:5
相关论文
共 48 条
[1]   Transcription sites are not correlated with chromosome territories in wheat nuclei [J].
Abranches, R ;
Beven, AF ;
Aragón-Alcaide, L ;
Shaw, PJ .
JOURNAL OF CELL BIOLOGY, 1998, 143 (01) :5-12
[2]  
Alberts B., 1994, MOL BIOL CELL
[3]   VISUALIZATION OF G1 CHROMOSOMES - A FOLDED, TWISTED, SUPERCOILED CHROMONEMA MODEL OF INTERPHASE CHROMATID STRUCTURE [J].
BELMONT, AS ;
BRUCE, K .
JOURNAL OF CELL BIOLOGY, 1994, 127 (02) :287-302
[4]  
Belmont AS, 1997, NATO ASI 3 HIGH TECH, V31, P261
[5]   LARGE-SCALE CHROMATIN STRUCTURAL DOMAINS WITHIN MITOTIC AND INTERPHASE CHROMOSOMES INVIVO AND INVITRO [J].
BELMONT, AS ;
BRAUNFELD, MB ;
SEDAT, JW ;
AGARD, DA .
CHROMOSOMA, 1989, 98 (02) :129-143
[6]   Visualizing the spatial relationships between defined DNA sequences and the axial region of extracted metaphase chromosomes [J].
Bickmore, WA ;
Oghene, K .
CELL, 1996, 84 (01) :95-104
[7]   Going the distance: A current view of enhancer action [J].
Blackwood, EM ;
Kadonaga, JT .
SCIENCE, 1998, 281 (5373) :60-63
[8]   ROLE OF CHROMOSOME TERRITORIES IN THE FUNCTIONAL COMPARTMENTALIZATION OF THE CELL-NUCLEUS [J].
CREMER, T ;
KURZ, A ;
ZIRBEL, R ;
DIETZEL, S ;
RINKE, B ;
SCHROCK, E ;
SPEICHER, MR ;
MATHIEU, U ;
JAUCH, A ;
EMMERICH, P ;
SCHERTHAN, H ;
RIED, T ;
CREMER, C ;
LICHTER, P .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1993, 58 :777-792
[9]   Large scale chromosomal movements during interphase progression in Drosophila [J].
Csink, AK ;
Henikoff, S .
JOURNAL OF CELL BIOLOGY, 1998, 143 (01) :13-22
[10]   THE METAPHASE SCAFFOLD IS HELICALLY FOLDED - SISTER CHROMATIDS HAVE PREDOMINANTLY OPPOSITE HELICAL HANDEDNESS [J].
DELATOUR, EB ;
LAEMMLI, UK .
CELL, 1988, 55 (06) :937-944