Spectrum of Eosinophilic End-Organ Manifestations

被引:59
作者
Akuthota, Praveen [1 ,2 ]
Weller, Peter F. [2 ,3 ]
机构
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Pulm Crit Care & Sleep Med, Boston, MA 02215 USA
[2] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Allergy & Inflammat, Boston, MA 02215 USA
[3] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Infect Dis, Boston, MA 02215 USA
基金
美国国家卫生研究院;
关键词
Eosinophils pathology; Eosinophils immunology; Humans; Pulmonary eosinophilia; Eosinophilic esophagitis; Hypereosinophilic syndrome; Churg-Strauss syndrome; Eosinophilic granulomatous vasculitis; HYPEREOSINOPHILIC SYNDROME; CARDIAC INVOLVEMENT; HUMAN LUNG; CARDIOVASCULAR MANIFESTATIONS; GRANULE PROTEINS; GRANULOMATOSIS; PNEUMONIA; ROLES; ESOPHAGITIS; FIBROSIS;
D O I
10.1016/j.iac.2015.04.002
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Eosinophil-associated disorders can affect practically all tissues and organs in the body, either individually or in combination. This article provides an overview of end-organ manifestations of eosinophilia and discusses selected organ systems, including the upper and lower respiratory, cardiovascular, gastrointestinal, nervous, dermatologic, and renal systems. Mechanisms by which eosinophilia leads to end-organ damage are also considered.
引用
收藏
页码:403 / +
页数:10
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