Antibacterial activity of polygodial

被引：51
|
作者：
Kubo, I [1 ]
Fujita, K [1 ]
Lee, SH [1 ]
Ha, TJ [1 ]
机构：
[1] Univ Calif Berkeley, Dept Environm Sci Policy & Management, Berkeley, CA 94720 USA
来源：
PHYTOTHERAPY RESEARCH | 2005年 / 19卷 / 12期
关键词：
polygodial; time kill curve; Bacillus subtilis; Staphylococcus aureus; Escherichia coli; Salmonella choleraesuis;
D O I：
10.1002/ptr.1777
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Polygodial was found to possess moderate antibacterial activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis with minimum bactericidal concentrations (MBC) of 100 and 100 mu g/mL (0.34 mm) and 1.00 and 50 mu g/mL, respectively. The time kill curve study showed that polygodial was bactericidal against B. subtilis and S. choleraesuis. However, there was a difference in its bactericidal action against endospore-forming B. subtilis and food-borne S. choleraesuis. Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码：1013 / 1017
页数：5
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