Antibacterial activity of polygodial

被引：51

作者：

Kubo, I ^{[1
]}

Fujita, K ^{[1
]}

Lee, SH ^{[1
]}

Ha, TJ ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Environm Sci Policy & Management, Berkeley, CA 94720 USA

来源：

PHYTOTHERAPY RESEARCH | 2005年 / 19卷 / 12期

关键词：

polygodial; time kill curve; Bacillus subtilis; Staphylococcus aureus; Escherichia coli; Salmonella choleraesuis;

D O I：

10.1002/ptr.1777

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Polygodial was found to possess moderate antibacterial activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis with minimum bactericidal concentrations (MBC) of 100 and 100 mu g/mL (0.34 mm) and 1.00 and 50 mu g/mL, respectively. The time kill curve study showed that polygodial was bactericidal against B. subtilis and S. choleraesuis. However, there was a difference in its bactericidal action against endospore-forming B. subtilis and food-borne S. choleraesuis. Copyright (c) 2005 John Wiley & Sons, Ltd.

引用

页码：1013 / 1017

页数：5

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