Immunoglobulin G4-related disease in the sigmoid colon in patient with severe colonic fibrosis and obstruction: A case report

被引:0
作者
Zhan, Wen-Li [1 ]
Liu, Liang [1 ]
Jiang, Wei [1 ]
He, Fang-Xun [1 ]
Qu, Hai-Tao [2 ]
Cao, Zhi-Xin [1 ]
Xu, Xiang-Shang [1 ,3 ]
机构
[1] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Gastrointestinal Surg, Wuhan 430030, Hubei, Peoples R China
[2] Henan Univ Tradit Chinese Med, Affiliated Hosp 1, Anorectal Dis Ctr, Zhengzhou 450000, Henan, Peoples R China
[3] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Gastrointestinal Surg, 1095 Jiefang Ave, Wuhan 430030, Hubei, Peoples R China
关键词
Immunoglobulin G4-related disease; Chronic colon disease; Plasma cells; Fibrosis; Obstruction; Case report; IGG4-RELATED DISEASE; AUTOIMMUNE PANCREATITIS; THERAPY;
D O I
10.4240/wjgs.v14.i10.1169
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
BACKGROUNDImmunoglobulin G4-related disease (IgG4-RD) is an immune-mediated condition characterized by abundant IgG4 positive plasma cells and fibrosis in the affected tissues. It affects most parts of the body; however, there are not many reports on IgG4-RD involving the colon.CASE SUMMARYA 50-year-old man complaining of intermittent fever for more than two years was referred to our hospital. Based on various investigations before surgery, we diagnosed him with chronic perforation of the sigmoid colon caused by inflammatory change or tumor. IgG blood tests before the operation suggested IgG4-RD, and postoperative pathology confirmed this prediction.CONCLUSIONWe present a patient with IgG4-RD with colon involvement, which is an uncommon site. This report will expand the understanding of IgG4-RD in unknown tissues.
引用
收藏
页码:1169 / 1178
页数:10
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