Privileged Phosphine-Based Metal-Organic Frameworks for Broad-Scope Asymmetric Catalysis

被引：229

作者：

Falkowski, Joseph M. ^{[1
]}

Sawano, Takahiro ^{[1
]}

Zhang, Teng ^{[1
]}

Tsun, Galen ^{[2
]}

Chen, Yuan ^{[3
]}

Lockard, Jenny V. ^{[3
]}

Lin, Wenbin ^{[1
]}

机构：

[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA

[2] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

[3] Rutgers State Univ, Dept Chem, Newark, NJ 07102 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 136卷 / 14期

基金：

美国国家科学基金会;

关键词：

HYBRID SOLIDS; HYDROGENATION; BINAP; 1,4-ADDITION; ACIDS; ARYL;

D O I：

10.1021/ja500090y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A robust and porous Zr metal-organic framework (MOF) based on a BINAP-derived dicarboxylate linker, BINAP-MOF, was synthesized and post-synthetically metalated with Ru and Rh complexes to afford highly enantioselective catalysts for important organic transformations. The Rh-functionalized MOF is not only highly enantioselective (up to >99% ee) but also 3 times as active as the homogeneous control. XAFS studies revealed that the Ru-functionalized MOF contains Ru-BINAP precatalysts with the same. coordination environment as the homogeneous Ru complex. The post-synthetically metalated BINAP-MOFs provide a versatile family of single-site solid catalysts for catalyzing a broad scope of asymmetric organic transformations, including addition of aryl and alkyl groups to alpha,beta-unsaturated ketones and hydrogenation of substituted alkene and carbonyl compounds.

引用

页码：5213 / 5216

页数：4

共 42 条

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