Advances in Radiation Oncology for the Management of Oropharyngeal Tumors

被引:5
作者
Gunn, G. Brandon [1 ]
Frank, Steven J. [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA
关键词
Radiation therapy; Oropharyngeal tumors; Head and neck cancer; Intensity-modulated proton therapy; Intensity-modulated radiation therapy; SQUAMOUS-CELL CARCINOMA; NECK-CANCER; RANDOMIZED-TRIAL; HEAD; RADIOTHERAPY; THERAPY; FRACTIONATION; CHEMOTHERAPY; SURVIVAL;
D O I
10.1016/j.otc.2013.04.004
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The major benefits of modern radiation therapy (eg, intensity-modulated [x-ray] radiation therapy [IMRT]) for oropharyngeal cancer are reduced xerostomia and better quality of life. Intensity-modulated proton therapy may provide additional advantages over IMRT by reducing radiation beam-path toxicities. Several acute and late treatment-related toxicities and symptom constellations must be kept in mind when designing and comparing future treatment strategies, particularly because currently most patients with oropharyngeal carcinoma present with human papillomavirus-positive disease and are expected to have a high probability of long-term survival after treatment.
引用
收藏
页码:629 / +
页数:16
相关论文
共 50 条
  • [31] Challenges and Complications in the Management of Advanced Oropharyngeal Carcinoma: Role of Post-Mortem Diagnosis and Future Perspectives
    Consalvo, Francesca
    De Simone, Matteo
    Scarpa, Alfonso
    Acerra, Alfonso
    Salzano, Francesco Antonio
    Fineschi, Vittorio
    Santurro, Alessandro
    [J]. JOURNAL OF CLINICAL MEDICINE, 2024, 13 (17)
  • [32] Final Report of NRG Oncology RTOG 0022: A Phase 1/2 Study of Conformal and Intensity Modulated Radiation for Oropharyngeal Cancer
    Garden, Adam S.
    Harris, Jonathan
    Eisbruch, Avraham
    Chao, K. S. Clifford
    Morrison, William H.
    Harari, Paul M.
    Swanson, Todd Allen
    Jones, Christopher U.
    Yom, Sue S.
    Spencer, Sharon A.
    Scrimger, Rufus
    Shenouda, George
    Shukla, Monica
    Lau, Harold Y.
    Mierzwa, Michelle
    Torres-Saavedra, Pedro
    Le, Quynh Thu
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : 333 - 340
  • [33] Advances in Radiation Oncology for the Treatment of Cervical Cancer
    Faye, Mame Daro
    Alfieri, Joanne
    [J]. CURRENT ONCOLOGY, 2022, 29 (02) : 928 - 944
  • [34] Advances in radiation oncology for metastatic bone disease
    Thariat, Juliette
    Fric, Daniele
    Kerr, Christine
    Leysalle, Axel
    Angellier, Gaelle
    Dejean, Catherine
    Tuillier, Titien
    Bensadoun, Rene-Jean
    Lagrange, Jean-Leon
    [J]. BULLETIN DU CANCER, 2013, 100 (11) : 1187 - 1197
  • [35] Radiation oncology: physics advances that minimize morbidity
    Allison, Ron R.
    Patel, Rajen M.
    McLawhorn, Robert A.
    [J]. FUTURE ONCOLOGY, 2014, 10 (15) : 2329 - 2344
  • [36] A real-world comparison of cisplatin vs cetuximab used concurrently with radiation in the treatment of locally advanced oropharyngeal carcinoma
    Fung, Andrea S.
    Afzal, Arfan Raheen
    Banerjee, Robyn
    Debenham, Brock
    Hao, Desiree
    [J]. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2021, 43 (01): : 153 - 163
  • [37] Pain management in radiation oncology
    Feuvret, L.
    Cuenca, X.
    Lavaud, P.
    Anane, S.
    Colin, E.
    [J]. CANCER RADIOTHERAPIE, 2013, 17 (5-6): : 523 - 527
  • [38] Advances of radiation oncology in China
    Meng Xue
    Yu Jin-ming
    [J]. CHINESE MEDICAL JOURNAL, 2009, 122 (19) : 2231 - 2235
  • [39] Hypofractionated radiation therapy alone for human papillomavirus-related oropharyngeal cancer
    Chen, Allen M.
    Harris, Jeremy P.
    Tjoa, Tjoson
    Haidar, Yarah
    Armstrong, William B.
    [J]. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2025, 47 (01): : 235 - 241
  • [40] Oncology Scan-The Concept of Personalized Medicine and the Radiation Response of Tumors
    Freeman, Michael L.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 88 (03): : 546 - 548