The Lack of Evidence for PET or PET/CT Surveillance of Patients with Treated Lymphoma, Colorectal Cancer, and Head and Neck Cancer: A Systematic Review

被引:22
作者
Patel, Kamal [1 ]
Hadar, Nira [1 ]
Lee, Jounghee [1 ]
Siegel, Barry A. [2 ,3 ]
Hillner, Bruce E. [4 ,5 ]
Lau, Joseph [1 ]
机构
[1] Tufts Med Ctr, Inst Clin Res & Hlth Policy Studies, Boston, MA USA
[2] Washington Univ, Sch Med, Mallinckrodt Inst Radiol, Div Nucl Med, St Louis, MO USA
[3] Washington Univ, Sch Med, Siteman Canc Ctr, St Louis, MO USA
[4] Virginia Commonwealth Univ, Dept Internal Med, Richmond, VA USA
[5] Virginia Commonwealth Univ, Massey Canc Ctr, Richmond, VA USA
关键词
surveillance; PET; PET/CT; lymphoma; colorectal; POSITRON-EMISSION-TOMOGRAPHY; SQUAMOUS-CELL CARCINOMA; FOLLOW-UP; F-18-FDG PET; FDG-PET/CT; IMPACT; RECURRENCE; UTILITY; HODGKIN; CT;
D O I
10.2967/jnumed.112.119362
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PET and PET/CT are widely used for surveillance of patients after cancer treatments. We conducted a systematic review to assess the diagnostic accuracy and clinical impact of PET and PET/CT used for surveillance in several cancers. Methods: We searched MEDLINE and Cochrane Library databases from 1996 to March 2012 for English-language studies of PET or PET/CT used for surveillance of patients with lymphoma, colorectal cancer, or head and neck cancer. We included prospective or retrospective studies that reported test accuracy and comparative studies that assessed clinical impact. Results: Twelve studies met our inclusion criteria: 6 lymphoma (n = 767 patients), 2 colorectal cancer (n = 96), and 4 head and neck cancer (n = 194). All studies lacked a uniform definition of surveillance and scan protocols. Half the studies were retrospective, and a third were rated as low quality. The majority reported sensitivities and specificities in the range of 90%-100%, although several studies reported lower results. The only randomized controlled trial, a colorectal cancer study with 65 patients in the surveillance arm, reported earlier detection of recurrences with PET and suggested improved clinical outcomes. Conclusion: There is insufficient evidence to draw conclusions on the clinical impact of PET or PET/CT surveillance for these cancers. The lack of standard definitions for surveillance, heterogeneous scanning protocols, and inconsistencies in reporting test accuracy preclude making an informed judgment on the value of PET for this potential indication.
引用
收藏
页码:1518 / 1527
页数:10
相关论文
共 38 条
[1]   High rates of surveillance imaging for treated diffuse large B-cell lymphoma: findings from a large national database [J].
Abel, Gregory A. ;
Vanderplas, Ann ;
Rodriguez, Maria A. ;
Crosby, Allison L. ;
Czuczman, Myron S. ;
Niland, Joyce C. ;
Gordon, Leo I. ;
Millenson, Michael ;
Zelenetz, Andrew D. ;
Friedberg, Jonathan W. ;
LaCasce, Ann S. .
LEUKEMIA & LYMPHOMA, 2012, 53 (06) :1113-1116
[2]   Does 18F-FDG PET/CT Improve the Detection of Posttreatment Recurrence of Head and Neck Squamous Cell Carcinoma in Patients Negative for Disease on Clinical Follow-up? [J].
Abgral, Ronan ;
Querellou, Solene ;
Potard, Gael ;
Le Roux, Pierre-Yves ;
Le Duc-Pennec, Alexandra ;
Marianovski, Remi ;
Pradier, Olivier ;
Bizais, Yves ;
Kraeber-Bodere, Francoise ;
Salaun, Pierre Y. .
JOURNAL OF NUCLEAR MEDICINE, 2009, 50 (01) :24-29
[3]   Prospective comparison of 18F-FDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer [J].
Adams, S ;
Baum, RP ;
Stuckensen, T ;
Bitter, K ;
Hör, G .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1998, 25 (09) :1255-1260
[4]  
[Anonymous], POSITRON EMISSION TO
[5]  
[Anonymous], SPEC REP POS EM TOM
[6]   Surveillance After Colorectal Cancer Resection: A Systematic Review [J].
Baca, Bilgi ;
Beart, Robert W., Jr. ;
Etzioni, David A. .
DISEASES OF THE COLON & RECTUM, 2011, 54 (08) :1036-1048
[7]  
Cohade C, 2003, J NUCL MED, V44, P1797
[8]   Clinical impact of, and prognostic stratification by, f-18 fdg pet/ct in head and neck mucosal squamous cell carcinoma [J].
Connell, Caroline A. ;
Corry, June ;
Milner, Alvin D. ;
Hogg, Annette ;
Hicks, Rodney J. ;
Rischin, Danny ;
Peters, Lester J. .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2007, 29 (11) :986-995
[9]   Role of 18FDG-PET/CT in detecting relapse during follow-up of patients with Hodgkin's lymphoma [J].
Crocchiolo, R. ;
Fallanca, F. ;
Giovacchini, G. ;
Ferreri, A. J. M. ;
Assanelli, A. ;
Verona, C. ;
Pescarollo, A. ;
Bregni, M. ;
Ponzoni, M. ;
Gianolli, L. ;
Fazio, F. ;
Ciceri, F. .
ANNALS OF HEMATOLOGY, 2009, 88 (12) :1229-1236
[10]   Efficacy of routine surveillance with positron emission tomography/computed tomography in aggressive non-Hodgkin lymphoma in complete remission: status in a single center [J].
El-Galaly, Tarec ;
Prakash, Vineet ;
Christiansen, Ilse ;
Madsen, Jakob ;
Johansen, Preben ;
Boegsted, Martin ;
Johnsen, Hans-Erik ;
Bukh, Anne .
LEUKEMIA & LYMPHOMA, 2011, 52 (04) :597-603