Synthesis of Secondary Metabolites from Higher Fungi

被引：7

作者：

Reck, Bernhard ^{[1
]}

Spiteller, Peter ^{[1
]}

机构：

[1] Univ Bremen, Inst Organ & Analyt Chem, D-28359 Bremen, Germany

来源：

SYNTHESIS-STUTTGART | 2015年 / 47卷 / 19期

关键词：

biological activity; biomimetic synthesis; fungi; natural products; total synthesis; ASYMMETRIC TOTAL-SYNTHESIS; 1ST TOTAL-SYNTHESIS; BIRDS NEST FUNGI; ENANTIOSELECTIVE TOTAL-SYNTHESIS; CHEMOENZYMATIC TOTAL-SYNTHESIS; GROWTH-FACTOR (NGF)-SYNTHESIS; SIGMATROPIC 1,2-ACYL SHIFT; FORMAL TOTAL-SYNTHESIS; (+/-)-HIRSUTIC ACID-C; NATURAL-PRODUCTS;

D O I：

10.1055/s-0034-1378774

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Higher fungi are a promising source of new bioactive natural products with great structural diversity, ranging from polyketides to terpenoids and alkaloids. Many of these structures are a challenge for synthetic organic chemists who have been inspired to develop new total syntheses. Nevertheless, reviews covering syntheses of fungal natural products are lacking. One aim of this review is to close this gap and to present a selection of more recent syntheses of fungal secondary metabolites from different structural classes. Secondly, this review intends to demonstrate that there are many more motivations for the synthesis of natural products than to confirm a proposed structure or to report the first total synthesis of a new natural product. Thirdly, this review is intended to stimulate the interest of organic chemists in the synthesis of fungal natural products.

引用

页码：2885 / 2911

页数：27

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