Chemiluminescence molecular probe with intrinsic auto-inductive amplification: incorporation of chemiexcitation in a quinone-methide elimination

被引：22

作者：

Gnaim, Samer ^{[1
]}

Shabat, Doron ^{[1
]}

机构：

[1] Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 21期

基金：

以色列科学基金会;

关键词：

SELF-IMMOLATIVE DENDRIMERS; SIGNAL AMPLIFICATION; DIAGNOSTIC PROBE; FLUORIDE IONS; DIOXETANE; DESIGN; LUCIFERIN; REAGENTS; MECHANISM; POLYMERS;

D O I：

10.1039/c8cc00521d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new signal amplification system with an auto-inductive mode of action and distinct chemiluminescence output was developed. The system is composed of a unique structural motif that combines a chemiexcitation mechanism with a quinone-methide elimination into a signal building block. As demonstrated with a probe designed to detect fluoride, an auto-inductive chemiluminescence signal amplification was obtained through self-immolative disassembly and light emission mechanisms.

引用

页码：2655 / 2658

页数：4

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