Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression

被引：31

作者：

Cialfi, S. ^{[1
,2
]}

Palermo, R. ^{[1
]}

Manca, S. ^{[1
]}

Checquolo, S. ^{[1
]}

Bellavia, D. ^{[1
]}

Pelullo, M. ^{[1
]}

Quaranta, R. ^{[1
]}

Donninic, C. ^{[2
]}

Gulino, A. ^{[1
]}

Screpanti, I. ^{[1
]}

Talora, C. ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dept Mol Med, Rome, Italy

[2] Univ Roma La Sapienza, Dept Pediat & Infantile Neuropsychiat, Rome, Italy

来源：

LEUKEMIA | 2013年 / 27卷 / 02期

关键词：

SIGNALING PATHWAY; LEUKEMIA; RESISTANCE; THERAPY; COMPLEX; CANCER;

D O I：

10.1038/leu.2012.192

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：485 / 488

页数：4

共 15 条

[1] CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia [J].

Buonamici, Silvia ;

Trimarchi, Thomas ;

Ruocco, Maria Grazia ;

Reavie, Linsey ;

Cathelin, Severine ;

Mar, Brenton G. ;

Klinakis, Apostolos ;

Lukyanov, Yevgeniy ;

Tseng, Jen-Chieh ;

Sen, Filiz ;

Gehrie, Eric ;

Li, Mengling ;

Newcomb, Elizabeth ;

Zavadil, Jiri ;

Meruelo, Daniel ;

Lipp, Martin ;

Ibrahim, Sherif ;

Efstratiadis, Argiris ;

Zagzag, David ;

Bromberg, Jonathan S. ;

Dustin, Michael L. ;

Aifantis, Iannis .

NATURE, 2009, 459 (7249) :1000-U129

[2]

Dang TP, 2012, ADV EXP MED BIOL, V727, P199, DOI 10.1007/978-1-4614-0899-4_15

[3] TAN-1, THE HUMAN HOMOLOG OF THE DROSOPHILA NOTCH GENE, IS BROKEN BY CHROMOSOMAL TRANSLOCATIONS IN T-LYMPHOBLASTIC NEOPLASMS [J].

ELLISEN, LW ;

BIRD, J ;

WEST, DC ;

SORENG, AL ;

REYNOLDS, TC ;

SMITH, SD ;

SKLAR, J .

CELL, 1991, 66 (04) :649-661

[4] Glucocorticoid use in acute lymphoblastic leukaemia [J].

Inaba, Hiroto ;

Pui, Ching-Hon .

LANCET ONCOLOGY, 2010, 11 (11) :1096-1106

[5] Notch in T-ALL: new players in a complex disease [J].

Koch, Ute ;

Radtke, Freddy .

TRENDS IN IMMUNOLOGY, 2011, 32 (09) :434-442

[6] The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism [J].

Kopan, Raphael ;

Ilagan, Ma. Xenia G. .

CELL, 2009, 137 (02) :216-233

[7] PHYSICAL ASSOCIATION AND FUNCTIONAL ANTAGONISM BETWEEN THE P65 SUBUNIT OF TRANSCRIPTION FACTOR NF-KAPPA-B AND THE GLUCOCORTICOID RECEPTOR [J].

RAY, A ;

PREFONTAINE, KE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (02) :752-756

[8] NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia [J].

Real, P. J. ;

Ferrando, A. A. .

LEUKEMIA, 2009, 23 (08) :1374-1377

[9] γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia [J].

Real, Pedro J. ;

Tosello, Valeria ;

Palomero, Teresa ;

Castillo, Mireia ;

Hernando, Eva ;

de Stanchina, Elisa ;

Sulis, Maria Luisa ;

Barnes, Kelly ;

Sawai, Catherine ;

Homminga, Irene ;

Meijerink, Jules ;

Aifantis, Iannis ;

Basso, Giuseppe ;

Cordon-Cardo, Carlos ;

Ai, Walden ;

Ferrando, Adolfo .

NATURE MEDICINE, 2009, 15 (01) :50-58

[10] The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia [J].

Thompson, Benjamin J. ;

Buonamici, Silvia ;

Sulis, Maria Luisa ;

Palomero, Teresa ;

Vilimas, Tomas ;

Basso, Giuseppe ;

Ferrando, Adolfo ;

Aifantis, Iannis .

JOURNAL OF EXPERIMENTAL MEDICINE, 2007, 204 (08) :1825-1835

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