Two New Sesquiterpene Lactones from Elephantopus tomentosus

被引：6
作者：
Wang Bei [1 ,2 ,3 ]
Mei Wenli [2 ]
Zuo Wenjian [2 ]
Zhao Youxing [2 ]
Dong Wenhua [2 ]
Liu Guodao [1 ]
Dai Haofu [2 ]
机构：
[1] Chinese Acad Trop Agr Sci, Trop Crops Genet Resources Inst, Danzhou 571737, Hainan, Peoples R China
[2] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China
[3] Hainan Univ, Hort & Garden Coll, Haikou 570228, Hainan, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2012年 / 30卷 / 06期
关键词：
sesquiterpene lactone; Elephantopus tomentosus; tomenphantopin E; tomenphantopin F; ANTITUMOR AGENTS; CYTOTOXIC GERMACRANOLIDES; ABSOLUTE STEREOCHEMISTRY; STRUCTURAL ELUCIDATION; MOLLIS; SCABER;
D O I：
10.1002/cjoc.201200231
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Phytochemical investigation on the whole plant of Elephantopus tomentosus Linn. led to the isolation of two new sesquiterpene lactones, tomenphantopin E (1) and tomenphantopin F (2). The new compounds were completely elucidated using a combination of 1D, 2D NMR technique (COSY, HSQC, HMBC and NOSEY), and HREIMS analysis.
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页码：1320 / 1322
页数：3
相关论文
共 16 条
  • [1] But PPH, 1997, PHYTOCHEMISTRY, V44, P113
  • [2] A new sesquiterpene lactone from Elephantopus mollis
    But, PPH
    Hon, PM
    Cao, H
    Che, CT
    [J]. PLANTA MEDICA, 1996, 62 (05) : 474 - 476
  • [3] Chen Y.L., 1985, FLORA REIPUBLICAE PO, V74, P43
  • [4] New sesquiterpene lactones from Elephantopus mollis and their leishmanicidal activities
    Fuchino, H
    Koide, T
    Takahashi, M
    Sekita, S
    Satake, M
    [J]. PLANTA MEDICA, 2001, 67 (07) : 647 - 653
  • [5] ANTITUMOR AGENTS .84. STRUCTURE AND ABSOLUTE STEREOCHEMISTRY OF TOMENPHANTOPIN-A AND TOMENPHANTOPIN-B, 2 CYTOTOXIC SESQUITERPENE LACTONES FROM ELEPHANTOPUS TOMENTOSUS
    HAYASHI, T
    KOYAMA, J
    MCPHAIL, AT
    LEE, KH
    [J]. PHYTOCHEMISTRY, 1987, 26 (04) : 1065 - 1068
  • [6] Antitumor agents.: 190.: Absolute stereochemistry of the cytotoxic germacranolides, tomenphantins A and B, from Elephantopus tomentosus
    Hayashi, T
    Nakano, T
    Kozuka, M
    McPhail, DR
    McPhail, AT
    Lee, KH
    [J]. JOURNAL OF NATURAL PRODUCTS, 1999, 62 (02): : 302 - 304
  • [7] TUMOR INHIBITORS .40. ISOLATION AND STRUCTURAL ELUCIDATION OF ELEPHANTIN AND ELEPHANTOPIN, 2 NOVEL SESQUITERPENOID TUMOR INHIBITORS FROM ELEPHANTOPUS ELATUS
    KUPCHAN, SM
    AYNEHCHI, Y
    CASSADY, JM
    SCHNOES, HK
    BURLINGAME, AL
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1969, 34 (12) : 3867 - +
  • [8] ANTI-TUMOR AGENTS .38. ISOLATION AND STRUCTURAL ELUCIDATION OF NOVEL GERMACRANOLIDES AND TRITERPENES FROM ELEPHANTOPUS-MOLLIS
    LEE, KH
    IBUKA, T
    FURUKAWA, H
    KOZUKA, M
    WU, RY
    HALL, IH
    HUANG, HC
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (09) : 1050 - 1056
  • [9] MOLEPHANTIN, A NOVEL CYTOTOXIC GERMACRANOLIDE FROM ELEPHANTOPUS-MOLLIS - X-RAY CRYSTAL-STRUCTURE
    LEE, KH
    FURUKAWA, H
    KOZUKA, M
    HUANG, HC
    LUHAN, PA
    MCPHAIL, AT
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1973, (14) : 476 - 477
  • [10] ANTITUMOR AGENTS .14. MOLEPHANTININ, A NEW POTENT ANTITUMOR SESQUITERPENE LACTONE FROM ELEPHANTOPUS-MOLLIS
    LEE, KH
    IBUKA, T
    HUANG, HC
    HARRIS, DL
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (06) : 1077 - 1078
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