Current and future strategies for treatment of glioma

被引：485

作者：

Bush, Nancy Ann Oberheim ^{[1
]}

Chang, Susan M. ^{[1
]}

Berger, Mitchel S. ^{[2
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol Surg, Div Neurooncol, San Francisco, CA USA

[2] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA USA

来源：

NEUROSURGICAL REVIEW | 2017年 / 40卷 / 01期

关键词：

Glioma; Glioblastoma; Pharmacology; Review; Stem cell; Targeted therapy; Treatment; Quality of life; CONVECTION-ENHANCED DELIVERY; CELL ADOPTIVE IMMUNOTHERAPY; GENOME-WIDE ASSOCIATION; QUALITY-OF-LIFE; TERM-FOLLOW-UP; FUNCTIONAL MRI; GLIOBLASTOMA-MULTIFORME; MALIGNANT GLIOMAS; PHASE-II; GRADE;

D O I：

10.1007/s10143-016-0709-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Gliomas are one of the most common types of primary brain tumors and have remained particularly challenging to treat. This review illustrates a multidisciplinary approach to the treatment of glioma and glioblastoma. We will review current advances in surgical approaches, novel imaging techniques, advanced molecular characterization of tumors and translational efforts for treatment. We will focus on current clinical trials as well as the pursuit of personalized or precision therapy. We will also comment on the importance of both quality of life of our patients and their care givers.

引用

页码：1 / 14

页数：14

共 84 条

[1] Glioblastoma: pathology, molecular mechanisms and markers [J].

Aldape, Kenneth ;

Zadeh, Gelareh ;

Mansouri, Sheila ;

Reifenberger, Guido ;

von Deimling, Andreas .

ACTA NEUROPATHOLOGICA, 2015, 129 (06) :829-848

[2] Glioblastoma multiforme: Pathogenesis and treatment [J].

Alifieris, Constantinos ;

Trafalis, Dimitrios T. .

PHARMACOLOGY & THERAPEUTICS, 2015, 152 :63-82

[3] Image guided surgery for the resection of brain tumours [J].

Barone, Damiano Giuseppe ;

Lawrie, Theresa A. ;

Hart, Michael G. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, (01)

[4] Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects [J].

Batchelor, Tracy T. ;

Reardon, David A. ;

de Groot, John F. ;

Wick, Wolfgang ;

Weller, Michael .

CLINICAL CANCER RESEARCH, 2014, 20 (22) :5612-5619

[5] Diffusion-tensor imaging-guided tracking of fibers of the pyramidal tract combined with intraoperative cortical stimulation mapping in patients with gliomas [J].

Berman, JI ;

Berger, MS ;

Mukherjee, P ;

Henry, RG .

JOURNAL OF NEUROSURGERY, 2004, 101 (01) :66-72

[6]

BLASBERG RG, 1977, CANCER TREAT REP, V61, P633

[7] Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial [J].

Bloch, Orin ;

Crane, Courtney A. ;

Fuks, Yelena ;

Kaur, Rajwant ;

Aghi, Manish K. ;

Berger, Mitchel S. ;

Butowski, Nicholas A. ;

Chang, Susan M. ;

Clarke, Jennifer L. ;

McDermott, Michael W. ;

Prados, Michael D. ;

Sloan, Andrew E. ;

Bruce, Jeffrey N. ;

Parsa, Andrew T. .

NEURO-ONCOLOGY, 2014, 16 (02) :274-279

[8]

Boxerman JL, 2006, AM J NEURORADIOL, V27, P859

[9] Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas [J].

Brat, Daniel J. ;

Verhaak, Roel G. W. ;

Al-dape, Kenneth D. ;

Yung, W. K. Alfred ;

Salama, Sofie R. ;

Cooper, Lee A. D. ;

Rheinbay, Esther ;

Miller, C. Ryan ;

Vitucci, Mark ;

Morozova, Olena ;

Robertson, A. Gordon ;

Noushmehr, Houtan ;

Laird, Peter W. ;

Cherniack, Andrew D. ;

Akbani, Rehan ;

Huse, Jason T. ;

Ciriello, Giovanni ;

Poisson, Laila M. ;

Barnholtz-Sloan, Jill S. ;

Berger, Mitchel S. ;

Brennan, Cameron ;

Colen, Rivka R. ;

Colman, Howard ;

Flanders, Adam E. ;

Giannini, Caterina ;

Grifford, Mia ;

Iavarone, Antonio ;

Jain, Rajan ;

Joseph, Isaac ;

Kim, Jaegil ;

Kasaian, Katayoon ;

Mikkelsen, Tom ;

Murray, Bradley A. ;

O'Neill, Brian Patrick ;

Pachter, Lior ;

Parsons, Donald W. ;

Sougnez, Carrie ;

Sulman, Erik P. ;

Vandenberg, Scott R. ;

Van Meir, Erwin G. ;

von Deimling, Andreas ;

Zhang, Hailei ;

Crain, Daniel ;

Lau, Kevin ;

Mallery, David ;

Morris, Scott ;

Paulauskis, Joseph ;

Penny, Robert ;

Shelton, Troy ;

Sherman, Mark .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (26) :2481-2498

[10] Stem-like Tumor-Initiating Cells Isolated from IL13Rα2 Expressing Gliomas Are Targeted and Killed by IL13-Zetakine-Redirected T Cells [J].

Brown, Christine E. ;

Starr, Renate ;

Aguilar, Brenda ;

Shami, Andrew F. ;

Martinez, Catalina ;

D'Apuzzo, Massimo ;

Barish, Michael E. ;

Forman, Stephen J. ;

Jensen, Michael C. .

CLINICAL CANCER RESEARCH, 2012, 18 (08) :2199-2209

← 1 2 3 4 5 6 7 8 9 →