Successful management of mucinous ovarian cancer by conservative surgery in week 6 of pregnancy: case report and literature review

被引:8
作者
He, Shan-yang [1 ]
Shen, Hong-wei [1 ]
Xu, Lin [2 ]
Li, Xiao-li [3 ]
Yao, Shu-zhong [1 ]
机构
[1] Sun Yat Sen Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, Guangzhou 510700, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Dept Microbiol, Zhongshan Sch Med, Guangzhou 510080, Guangdong, Peoples R China
[3] Memory HeXiang Hosp, Dept Obstet & Gynecol, Guangzhou 511400, Guangdong, Peoples R China
关键词
Pregnancy; Ovarian cancer; Cytoreductive surgery; Chemotherapy; OF-THE-LITERATURE; GYNECOLOGIC CANCERS; CHEMOTHERAPY; CARCINOMA; GUIDELINES;
D O I
10.1007/s00404-012-2490-4
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The management of ovarian cancer during pregnancy is still a big challenge, mostly due to the reciprocal impacts between cancer and pregnancy. The objective of this article is to present a rare case of maternal ovarian adenocarcinoma and review published similar cases about this clinical condition. Here we report a rare case of maternal ovarian adenocarcinoma detected during gestational week 6, with good pregnancy outcome treated with conservative surgery. A case of maternal ovarian adenocarcinoma (stage I) was detected in week 6 of pregnancy receiving conservative surgery without chemotherapy. In week 39 of pregnancy, due to relapse of the cancer, the patient underwent excision of the isolated tumor, and gave birth to a healthy baby through cesarian section. After that, the patient received cytoreductive surgery associated with six chemotherapy. The patient was finally diagnosed as epithelial ovarian cancer stage IIIC, and had survived more than 5 years without relapse. The successful experience from this case suggested that pregnancy complicated with early ovarian cancer receiving conservative surgery could continue to pregnancy and the effect of cesarian section followed with cytoreductive surgery associated with six chemotherapy at full term was still satisfied.
引用
收藏
页码:989 / 993
页数:5
相关论文
共 23 条
[1]   Serum tumour markers in gynaecological cancers [J].
Aggarwal, Pakhee ;
Kehoe, Sean .
MATURITAS, 2010, 67 (01) :46-53
[2]   Gynecologic Cancers in Pregnancy: Guidelines of an International Consensus Meeting [J].
Amant, Frederic ;
Van Calsteren, Kristel ;
Halaska, Michael J. ;
Beijnen, Jos ;
Lagae, Lieven ;
Hanssens, Myriam ;
Heyns, Liesbeth ;
Lannoo, Lore ;
Ottevanger, Nelleke P. ;
Bogaert, Walter Vanden ;
Ungar, Laszlo ;
Vergote, Ignace ;
du Bois, Andreas .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2009, 19 :S1-S12
[3]  
Baek Su-Jin, 2008, J Gynecol Oncol, V19, P223, DOI 10.3802/jgo.2008.19.4.223
[4]   Ovarian carcinoma associated with pregnancy: A clinicopathologic analysis of 23 cases and review of the literature [J].
Behtash N. ;
Karimi Zarchi M. ;
Modares Gilani M. ;
Ghaemmaghami F. ;
Mousavi A. ;
Ghotbizadeh F. .
BMC Pregnancy and Childbirth, 8 (1)
[5]   Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer [J].
Bertenshaw, Greg P. ;
Yip, Ping ;
Seshaiah, Partha ;
Zhao, Jinghua ;
Chen, Tzong-Hao ;
Wiggins, Wesley S. ;
Mapes, James P. ;
Mansfield, Brian C. .
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2008, 17 (10) :2872-2881
[6]   Surgical management of recurrent ovarian cancer: The advantage of collaborative surgical management and a multidisciplinary approach [J].
Burton, Elizabeth ;
Chase, Dana ;
Yamamoto, Maki ;
de Guzman, Jayson ;
Imagawa, David ;
Berman, Michael L. .
GYNECOLOGIC ONCOLOGY, 2011, 120 (01) :29-32
[7]   Ovarian cancer in younger vs older women: a population-based analysis [J].
Chan, J. K. ;
Urban, R. ;
Cheung, M. K. ;
Osann, K. ;
Husain, A. ;
Teng, N. N. ;
Kapp, D. S. ;
Berek, J. S. ;
Leiserowitz, G. S. .
BRITISH JOURNAL OF CANCER, 2006, 95 (10) :1314-1320
[8]  
Huang HP, 2004, EUR J GYNAECOL ONCOL, V25, P635
[9]  
KATZ VL, 1993, J REPROD MED, V38, P907
[10]   TREATMENT OF ADVANCED EPITHELIAL OVARIAN-CARCINOMA IN PREGNANCY WITH CISPLATIN-BASED CHEMOTHERAPY [J].
KING, LA ;
NEVIN, PC ;
WILLIAMS, PP ;
CARSON, LF .
GYNECOLOGIC ONCOLOGY, 1991, 41 (01) :78-80