LABEL-FREE ELECTROCHEMICAL DETECTION OF TETRACYCLINE BY AN APTAMER NANO-BIOSENSOR

被引：31

作者：

Zhang, Juankun ^{[1
]}

Wu, Yan ^{[1
]}

Zhang, Binbin ^{[1
]}

Li, Min ^{[1
]}

Jia, Shiru ^{[1
]}

Jiang, Shuhai ^{[1
]}

Zhou, Hao ^{[1
]}

Zhang, Yi ^{[1
]}

Zhang, Chaozheng ^{[1
]}

Turner, Anthony P. F. ^{[2
]}

机构：

[1] Tianjin Univ Sci & Technol, Tianjin Key Lab Ind Microbiol, Minist Educ, Coll Biotechnol, Tianjin 300457, Peoples R China

[2] Linkoping Univ, Biosensors & Bioelect Ctr, IFM, Linkoping, Sweden

来源：

ANALYTICAL LETTERS | 2012年 / 45卷 / 09期

关键词：

Aptamer; Biosensor; Impedance; Nano-porous silicon; Tetracycline; SILICON PHOTONIC CRYSTALS; POROUS-SILICON; MOLECULES; MATRIX; CHIP;

D O I：

10.1080/00032719.2012.670784

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel aptamer nano-porous silicon (PS) biosensor was investigated for the rapid determination of tetracyclines. Electrochemical impedance spectroscopy (EIS) was used to analyze the behavior of the sensor. The specific binding of tetracycline to the aptamer biosensor led to a decrease in impedance. The corresponding impedance spectra (Nyquist plots) were obtained when serial concentrations of tetracycline were added into the system. An equivalent electrical circuit was used to fit the impedance data. The linear range of the sensor was 2.1-62.4 nM.

引用

页码：986 / 992

页数：7

共 24 条

[1] A novel electrochemical detection method for aptamer biosensors [J].