Structure of a polysaccharide from Urtica fissa determined by NMR spectra

被引：9

作者：

Wang, Yan-Liang ^{[1
,2
]}

Li, Li ^{[1
]}

Cheng, Xiao-Chen ^{[1
]}

Lu, Yu-Xin ^{[1
]}

Zhang, Qing-Lin ^{[1
]}

机构：

[1] Beijing Inst Radiat Med, Beijing 100850, Peoples R China

[2] Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2012年 / 14卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Urtica fissa; polysaccharide; NMR experiment; structure; URINARY-TRACT SYMPTOMS; STINGING NETTLE ROOTS; LONG-TERM EFFICACY; DOUBLE-BLIND; EXTRACT; DIOICA; COMBINATION; MULTICENTER; HYPERPLASIA; FRACTION;

D O I：

10.1080/10286020.2012.681050

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A polysaccharide, isolated and purified from the aqueous extract of nettle plant Urtica fissa, was found to consist of D-glucose and D-arabinose. Molecular weight was determined to be Mn 4140. The NMR experiments (H-1, C-13, H-1-H-1 COSY, TOCSY, HSQC, NOESY, and HMBC) revealed the structure as the following repeating unit: -> 6)-alpha-D-Glcp-(1 -> 6)-alpha-D-Glcp-(1 -> 6)-beta-D-Glcp - (1 -> 5)-beta-D-Araf-(1 -> 3)-beta-D-Glcp-(1 ->

引用

页码：592 / 595

页数：4

共 13 条

[1] In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L. [J].

Akbay, P ;

Basaran, AA ;

Undeger, U ;

Basaran, N .

PHYTOTHERAPY RESEARCH, 2003, 17 (01) :34-37

[2] Long-term efficacy and safety of PRO 160/120 (a combination of Sabal and Urtica extract) in patients with lower urinary tract symptoms (LUTS) [J].

Bondarenko, B ;

Walther, C ;

Funk, P ;

Schläfke, S ;

Engelmann, U .

PHYTOMEDICINE, 2003, 10 :53-55

[3] CAFFEIC ACID-ESTERS FROM URTICA-DIOICA AND U-URENS [J].

BUDZIANOWSKI, J .

PLANTA MEDICA, 1991, 57 (05) :507-507

[4] FLAVONOL GLYCOSIDES FROM URTICA-DIOICA [J].

CHAURASIA, N ;

WICHTL, M .

PLANTA MEDICA, 1987, (05) :432-434

[5]

Lichius JJ, 1999, PHARMAZIE, V54, P768

[6] Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms -: A placebo-controlled, double-blind, multicenter trial [J].

Lopatkin, N ;

Sivkov, A ;

Walther, C ;

Schläfke, S ;

Medvedev, A ;

Avdeichuk, J ;

Golubev, G ;

Melnik, K ;

Elenberger, N ;

Engelmann, U .

WORLD JOURNAL OF UROLOGY, 2005, 23 (02) :139-146

[7] Structural investigation of a polysaccharide (Fr. II) isolated from the aqueous extract of an edible mushroom, Pleurotus sajor-caju [J].

Pramanik, M ;

Mondal, S ;

Chakraborty, I ;

Rout, D ;

Islam, SS .

CARBOHYDRATE RESEARCH, 2005, 340 (04) :629-636

[8]

Safarinejd Mohammad Reza, 2005, Journal of Herbal Pharmacotherapy, V5, P1, DOI [10.1080/J157v05n04_01, 10.1300/J157v05n04_01]

[9] Extract of stinging nettle roots (Bazoton®-uno) in long-term treatment of benign prostatic syndrome (BPS).: Results of a randomized, double-blind, placebo-controlled multicenter study after 12 months [J].

Schneider, T ;

Rübben, H .

UROLOGE A, 2004, 43 (03) :302-306

[10] Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG) [J].

Schottner, M ;

Gansser, D ;

Spiteller, G .

PLANTA MEDICA, 1997, 63 (06) :529-532

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