Improved Base Editor for Efficiently Inducing Genetic Variations in Rice with CRISPR/Cas9-Guided Hyperactive hAID Mutant

被引:177
作者
Ren, Bin [1 ,2 ]
Yan, Fang [1 ]
Kuang, Yongjie [1 ]
Li, Na [1 ]
Zhang, Dawei [2 ]
Zhou, Xueping [3 ]
Lin, Honghui [2 ]
Zhou, Huanbin [1 ]
机构
[1] Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China
[2] Sichuan Univ, Coll Life Sci, Minist Educ, Key Lab Bioresource & Ecoenvironm, Chengdu 610065, Sichuan, Peoples R China
[3] Zhejiang Univ, Inst Biotechnol, State Key Lab Rice Biol, Hangzhou 310058, Zhejiang, Peoples R China
基金
国家重点研发计划; 中国国家自然科学基金;
关键词
TARGET BASE; DNA;
D O I
10.1016/j.molp.2018.01.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:623 / 626
页数:4
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