Diagnostic Assays for Identification of Microorganisms and Antimicrobial Resistance Determinants Directly from Positive Blood Culture Broth

被引：24

作者：

Pence, Morgan A. ^{[1
]}

TeKippe, Erin McElvania ^{[1
]}

Burnham, Carey-Ann D. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Pathol & Immunol, Div Lab & Genom Med, St Louis, MO 63110 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2013年 / 33卷 / 03期

关键词：

Blood culture; Molecular diagnostics; Staphylococcus aureus; MRSA; Rapid pathogen detection; Bacteremia; DESORPTION IONIZATION-TIME; IN-SITU HYBRIDIZATION; POLYMERASE-CHAIN-REACTION; FLIGHT MASS-SPECTROMETRY; GRAM-NEGATIVE RODS; RIBOSOMAL-RNA GENE; SUSCEPTIBLE STAPHYLOCOCCUS-AUREUS; BD PHOENIX SYSTEM; RAPID IDENTIFICATION; METHICILLIN-RESISTANT;

D O I：

10.1016/j.cll.2013.03.010

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The detection of blood stream infections is one of the most important functions of the clinical microbiology laboratory. Sepsis is a clinical emergency, and mortality increases if commencement of appropriate antimicrobial therapy is delayed. Automated blood culture systems are the most sensitive approach for detection of the causative agent of sepsis. Several laboratory methods have been developed to expedite identification of organisms directly from positive blood culture broth. The principle and analytical performance characteristics of these methods are described in this review.

引用

页码：651 / +

页数：36

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