Treating the Elderly Stroke Patient Complications, Controversies, and Best Care Metrics

被引：7

作者：

Heitsch, Laura E. ^{[1
]}

Panagos, Peter D. ^{[1
,2
]}

机构：

[1] Washington Univ, Sch Med, Div Emergency Med, Dept Neurol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA

来源：

CLINICS IN GERIATRIC MEDICINE | 2013年 / 29卷 / 01期

关键词：

Acute ischemic stroke; Elderly stroke; Thrombolysis; Emergency care/treatment; tPA; Intra-arterial; ACUTE ISCHEMIC-STROKE; TISSUE-PLASMINOGEN ACTIVATOR; RANDOMIZED CONTROLLED-TRIAL; AGED; 80; YEARS; COOPERATIVE ACUTE STROKE; INTRAVENOUS RT-PA; ATRIAL-FIBRILLATION; HEMORRHAGIC TRANSFORMATION; INTRACEREBRAL HEMORRHAGE; THROMBOLYTIC THERAPY;

D O I：

10.1016/j.cger.2012.10.001

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Acute stroke is a devastating disease that affects almost 800,000 Americans annually. Worldwide, the incidence of stroke is rapidly increasing. Although stroke can affect all age groups, patients over age 80 are at much higher risk for ischemic stroke. Despite this, there are disparities in thrombolytic treatment rates, and as well as outcomes, between elderly stroke patients and their younger counterparts. This article discusses what is currently known about the elderly stroke patient for a greater understanding of the disease burden, research limitations and potential treatment options.

引用

页码：231 / +

页数：26

共 85 条

[1] Stroke Treatment Academic Industry Roundtable (STAIR) Recommendations for Maximizing the Use of Intravenous Thrombolytics and Expanding Treatment Options With Intra-arterial and Neuroprotective Therapies [J].

Albers, Gregory W. ;

Goldstein, Larry B. ;

Hess, David C. ;

Wechsler, Lawrence R. ;

Furie, Karen L. ;

Gorelick, Philip B. ;

Hurn, Patty ;

Liebeskind, David S. ;

Nogueira, Raul G. ;

Saver, Jeffrey L. .

STROKE, 2011, 42 (09) :2645-2650

[2] Is Thrombolysis Safe in the Elderly? Analysis of a National Database [J].

Alshekhlee, Amer ;

Mohammadi, Afshin ;

Mehta, Sonal ;

Edgell, Randall C. ;

Vora, Nirav ;

Feen, Eli ;

Kale, Sushant ;

Shakir, Zaid A. ;

Cruz-Flores, Salvador .

STROKE, 2010, 41 (10) :2259-2264

[3]

[Anonymous], P NAT S RAP ID TREAT

[4]

[Anonymous], STROKE

[5] Risks and benefits of thrombolysis in the elderly [J].

Asdaghi, Negar ;

Butcher, Kenneth S. ;

Hill, Michael D. .

INTERNATIONAL JOURNAL OF STROKE, 2012, 7 (02) :142-149

[6] Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility [J].

Barber, PA ;

Zhang, J ;

Demchuk, AM ;

Hill, MD ;

Buchan, AM .

NEUROLOGY, 2001, 56 (08) :1015-1020

[7] Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (≥80 years) stroke patients [J].

Berrouschot, J ;

Röther, J ;

Glahn, J ;

Kucinski, T ;

Fiehler, J ;

Thomalla, G .

STROKE, 2005, 36 (11) :2421-2425

[8] Intravenous thrombolysis in acute ischaemic stroke: a systematic review and meta-analysis to aid decision making in patients over 80 years of age [J].

Bhatnagar, Pallav ;

Sinha, Devesh ;

Parker, Richard A. ;

Guyler, Paul ;

O'Brien, Anthony .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2011, 82 (07) :712-717

[9] Intravenous thrombolysis for acute cerebral ischaemia in old stroke patients ≥80 years of age [J].

Boulouis, Gregoire ;

Dumont, Frederic ;

Cordonnier, Charlotte ;

Bodenant, Marie ;

Leys, Didier ;

Henon, Hilde .

JOURNAL OF NEUROLOGY, 2012, 259 (07) :1461-1467

[10] Intravenous TPA for very old stroke patients [J].

Chen, CI ;

Iguchi, Y ;

Grotta, JC ;

Garami, Z ;

Uchino, K ;

Shaltoni, H ;

Alexandrov, AV .

EUROPEAN NEUROLOGY, 2005, 54 (03) :140-144

← 1 2 3 4 5 6 7 8 9 →