Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation

被引：117

作者：

Park, Jihye ^{[1
]}

Kim, Minyoung ^{[1
]}

Sharma, Satyasheel ^{[1
]}

Park, Eonjeong ^{[1
]}

Kim, Aejin ^{[1
]}

Lee, Sang Hwi ^{[1
]}

Kwak, Jong Hwan ^{[1
]}

Jung, Young Hoon ^{[1
]}

Kim, In Su ^{[1
]}

机构：

[1] Sungkyunkwan Univ, Sch Pharm, Suwon 440746, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 16期

基金：

新加坡国家研究基金会;

关键词：

OXIDATIVE ORTHO-ACYLATION; TERT-BUTYL HYDROPEROXIDE; O-METHYL OXIMES; SIMPLE ARENES; PALLADIUM COMPLEXES; ROOM-TEMPERATURE; ALDEHYDES; ACETANILIDES; DERIVATIVES; BENZAMIDES;

D O I：

10.1039/c3cc38764j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium-catalyzed decarboxylative acylation of phenylacetamides with alpha-oxocarboxylic acids via C-H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.

引用

页码：1654 / 1656

页数：3

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