Recent advances in the enantioseparation promoted by ionic liquids and their resolution mechanisms

被引：26

作者：

Nie, Lirong ^{[1
]}

Yohannes, Alula ^{[2
]}

Yao, Shun ^{[2
]}

机构：

[1] Univ Shanghai Sci & Technol, Sch Med Instrument & Food Engn, 516 Jungong Rd, Shanghai 200093, Peoples R China

[2] Sichuan Univ, Sch Chem Engn, 24 South Sect 1,Yihuan Rd, Chengdu 610065, Peoples R China

来源：

JOURNAL OF CHROMATOGRAPHY A | 2020年 / 1626卷

基金：

中国国家自然科学基金;

关键词：

Ionic liquids; Enantioseparation; Chromatography; Chiral extraction; Capillary electrophoresis; Mechanism; CHIRAL STATIONARY-PHASE; CAPILLARY-ELECTROPHORESIS SYSTEM; HYDROXYPROPYL-BETA-CYCLODEXTRIN; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; AQUEOUS 2-PHASE SYSTEMS; AMINO-ACIDS; ENANTIOMERIC SEPARATION; SYNERGISTIC SYSTEM; PROPRANOLOL ENANTIOMERS; CLINDAMYCIN PHOSPHATE;

D O I：

10.1016/j.chroma.2020.461384

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

More and more various chemical media are being applied in enantioseparation; among them, ionic liquids (ILs) have attracted the long-term attention in this decade as green designable solvents. This paper provides comprehensive overview for the applications of ILs in chiral extraction, gas chromatography, liquid chromatography, capillary electrophoresis and other techniques for enantioseparation. Additionally, the important resolution mechanisms based on ILs have also been summarized and discussed. This review focuses on the latest development of enantioseparation methods by using ILs in various modes, leading to meaningful and valuable information to related fields and thus promotes further research and application of reported methods. (c) 2020 Elsevier B.V. All rights reserved.

引用

页数：25

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