Antiviral activity of an aqueous extract of the cyanobacterium Microcystis aeruginosa

被引:0
作者
Nowotny, A [1 ]
Mentel, R [1 ]
Wegner, U [1 ]
Mundt, S [1 ]
Lindequist, U [1 ]
机构
[1] UNIV GREIFSWALD,INST MED MICROBIOL,D-17487 GREIFSWALD,GERMANY
关键词
Microcystis aeruginosa; antiviral activity; influenza; trypsin inhibition;
D O I
10.1002/(SICI)1099-1573(199703)11:2<93::AID-PTR46>3.0.CO;2-G
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The crude aqueous extract of a field collected strain of Microcystis aeruginosa (Kutz) showed antiviral activity against influenza A virus. The concentration for 50% inhibition of virus replication in MDCK cells was 11 mu g dry extract/mL. The virus specific protein synthesis decreased if the extract was present over the whole time of replication. Furthermore protease inhibitory activity was estimated for the crude aqueous extract and subextracts. (C) 1997 by John Wiley & Sons, Ltd.
引用
收藏
页码:93 / 96
页数:4
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