Xidaosterols A and B, two new steroids with unusual α-keto-enol functionality from the South China Sea sponge Neopetrosia chaliniformis

被引：8
作者：
Chen, Bao [1 ,2 ]
Gu, Yu-Cheng [3 ]
de Voogd, Nicole J. [4 ,5 ]
Wang, Chang-Yun [2 ]
Guo, Yue-Wei [1 ,6 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai, Peoples R China
[2] Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Minist Educ China, Qingdao, Peoples R China
[3] Jealotts Hill Int Res Ctr, Syngenta, Bracknell, Berks, England
[4] Nat Biodivers Ctr, Leiden, Netherlands
[5] Leiden Univ, Inst Environm Sci, Leiden, Netherlands
[6] Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, Qingdao, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 08期
基金：
中国国家自然科学基金;
关键词：
sponge; Neopetrosia chaliniformis; steroids;
D O I：
10.1080/14786419.2020.1837820
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new C29 steroids, xidaosterols A (1) and B (2), characterised by a common unusual alpha-keto-enol functionality bearing A-ring, together with three related known ones (3-5), were isolated from the South China Sea sponge Neopetrosia chaliniformis. Their structures were elucidated by extensive spectroscopic analyses and comparison with the spectral data reported in the literature, Xidaosterol B is an A-nor derivative of 1.
引用
收藏
页码：1941 / 1947
页数：7
相关论文
共 19 条
  • [1] Exiguaquinol:: A novel pentacyclic hydroquinone from Neopetrosia exigua that inhibits Helicobacter pylori murl
    Leone, Priscila de Almeida
    Carroll, Anthony R.
    Towerzey, Leanne
    King, Gordon
    McArdle, Bernadette M.
    Kern, Gunther
    Fisher, Stewart
    Hooper, John N. A.
    Quinn, Ronald J.
    [J]. ORGANIC LETTERS, 2008, 10 (12) : 2585 - 2588
  • [2] New New cytotoxic ergostane-type sterols from the Chinese soft coral Sinularia sp.
    Jiang, Cheng-Shi
    Ru, Tong
    Huan, Xia-Juan
    Miao, Ze-Hong
    Guo, Yue-Wei
    [J]. STEROIDS, 2019, 149
  • [3] Steroids from the soft coral Dendronephthya sp.
    Li, GQ
    Deng, ZW
    Guan, HS
    van Ofwegen, LP
    Proksch, P
    Lin, WH
    [J]. STEROIDS, 2005, 70 (01) : 13 - 18
  • [4] Isolation of antibacterial diterpenoids from Cryptomeria japonica bark
    Li, Wen-Hsin
    Chang, Shang-Tzen
    Chang, Shan-Chwen
    Chang, Hui-Ting
    [J]. NATURAL PRODUCT RESEARCH, 2008, 22 (12) : 1085 - 1093
  • [5] 9′-Epi-3β,3′β-dimethylxestospongin C, a New Macrocyclic Diamine Alkaloid from the Hainan Sponge Neopetrosia exigua
    Li, Yan
    Qin, Song
    Guo, Yue-Wei
    Gu, Yu-Cheng
    van Soest, Rob W. M.
    [J]. PLANTA MEDICA, 2011, 77 (02) : 179 - 181
  • [6] Liu H., 2004, MAR DRUGS, V2, P154, DOI [10.3390/md204154, DOI 10.3390/MD204154]
  • [7] Constituents from Limonia crenulata
    Niu, XM
    Li, SH
    Peng, LY
    Lin, ZW
    Rao, GX
    Sun, HD
    [J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2001, 3 (04) : 299 - 311
  • [8] Renieramycin J, a highly cytotoxic tetrahydroisoquinoline alkaloid, from a marine sponge Neopetrosia sp.
    Oku, N
    Matsunaga, S
    van Soest, RWM
    Fusetani, N
    [J]. JOURNAL OF NATURAL PRODUCTS, 2003, 66 (08): : 1136 - 1139
  • [9] Cytotoxic components from the Xisha sponge Fascaplysinopsis reticulata
    Qin, Guo-Fei
    Tang, Xu-Li
    de Voogd, Nicole J.
    Li, Ping-Lin
    Li, Guo-Qiang
    [J]. NATURAL PRODUCT RESEARCH, 2020, 34 (06) : 790 - 796
  • [10] Crellasterones A and B: A-Norsterol Derivatives from the New Caledonian Sponge Crella incrustans
    Ragini, Kavita
    Piggott, Andrew M.
    Karuso, Peter
    [J]. MARINE DRUGS, 2017, 15 (06):
12