Xidaosterols A and B, two new steroids with unusual α-keto-enol functionality from the South China Sea sponge Neopetrosia chaliniformis

被引:8
作者
Chen, Bao [1 ,2 ]
Gu, Yu-Cheng [3 ]
de Voogd, Nicole J. [4 ,5 ]
Wang, Chang-Yun [2 ]
Guo, Yue-Wei [1 ,6 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai, Peoples R China
[2] Ocean Univ China, Sch Med & Pharm, Key Lab Marine Drugs, Minist Educ China, Qingdao, Peoples R China
[3] Jealotts Hill Int Res Ctr, Syngenta, Bracknell, Berks, England
[4] Nat Biodivers Ctr, Leiden, Netherlands
[5] Leiden Univ, Inst Environm Sci, Leiden, Netherlands
[6] Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, Qingdao, Peoples R China
基金
中国国家自然科学基金;
关键词
sponge; Neopetrosia chaliniformis; steroids;
D O I
10.1080/14786419.2020.1837820
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Two new C29 steroids, xidaosterols A (1) and B (2), characterised by a common unusual alpha-keto-enol functionality bearing A-ring, together with three related known ones (3-5), were isolated from the South China Sea sponge Neopetrosia chaliniformis. Their structures were elucidated by extensive spectroscopic analyses and comparison with the spectral data reported in the literature, Xidaosterol B is an A-nor derivative of 1.
引用
收藏
页码:1941 / 1947
页数:7
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