Activation by attention of the human reticular formation and thalamic intralaminar nuclei

被引：476

作者：

Kinomura, S ^{[1
]}

Larsson, J ^{[1
]}

Gulyas, B ^{[1
]}

Roland, PE ^{[1
]}

机构：

[1] KAROLINSKA INST,DEPT NEUROSCI,DIV HUMAN BRAIN RES,S-17177 STOCKHOLM,SWEDEN

来源：

SCIENCE | 1996年 / 271卷 / 5248期

关键词：

D O I：

10.1126/science.271.5248.512

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

It has been known for over 45 years that electrical stimulation of the midbrain reticular formation and of the thalamic intralaminar nuclei of the brain alerts animals. However, lesions of these sectors fail to impair arousal and vigilance in some cases, making the role of the ascending activating reticular system controversial. Here, a positron emission tomographic study showed activation of the midbrain reticular formation and of thalamic intralaminar nuclei when human participants went from a relaxed awake state to an attention-demanding reaction-time task. These results confirm the role of these areas of the brain and brainstem in arousal and vigilance.

引用

页码：512 / 515

页数：4

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