Initial Approach to Patients with a Newly Diagnosed Solitary Brain Metastasis

被引：3

作者：

Liu, James K. C. ^{[1
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Neurooncol, 12902 USF Magnolia Dr,CSB 6141, Tampa, FL 33612 USA

来源：

NEUROSURGERY CLINICS OF NORTH AMERICA | 2020年 / 31卷 / 04期

关键词：

Solitary brain metastasis; Surgical resection; Stereotactic radiosurgery; Whole-brain radiation therapy; POSTOPERATIVE STEREOTACTIC RADIOSURGERY; RADIATION-THERAPY; CEREBRAL METASTASES; SURGICAL RESECTION; LEPTOMENINGEAL DISEASE; COMPARATIVE RISK; LUNG-CANCER; RADIOTHERAPY; SURVIVAL; SURGERY;

D O I：

10.1016/j.nec.2020.05.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Solitary brain metastasis is defined by a single metastatic brain lesion as the only site of metastasis. The initial approach to this condition consists of radiographical evaluation to establish diagnosis, followed by assessment of functional and prognostic status. Neurologic symptom management consists of using dexamethasone and antiepileptic medications. Treatment consists of a combination of surgical and radiation therapy. Surgical treatment is indicated where there is a need for tissue diagnosis or immediate alleviation of neurologic symptoms and mass effect. Stereotactic radiosurgery has become an effective treatment modality. Whole-brain radiation therapy may have a role as an adjunctive therapy. © 2020 Elsevier Inc.

引用

收藏

页码：489 / 503

页数：15

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