Initial Approach to Patients with a Newly Diagnosed Solitary Brain Metastasis

被引：3

作者：

Liu, James K. C. ^{[1
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Neurooncol, 12902 USF Magnolia Dr,CSB 6141, Tampa, FL 33612 USA

来源：

NEUROSURGERY CLINICS OF NORTH AMERICA | 2020年 / 31卷 / 04期

关键词：

Solitary brain metastasis; Surgical resection; Stereotactic radiosurgery; Whole-brain radiation therapy; POSTOPERATIVE STEREOTACTIC RADIOSURGERY; RADIATION-THERAPY; CEREBRAL METASTASES; SURGICAL RESECTION; LEPTOMENINGEAL DISEASE; COMPARATIVE RISK; LUNG-CANCER; RADIOTHERAPY; SURVIVAL; SURGERY;

D O I：

10.1016/j.nec.2020.05.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Solitary brain metastasis is defined by a single metastatic brain lesion as the only site of metastasis. The initial approach to this condition consists of radiographical evaluation to establish diagnosis, followed by assessment of functional and prognostic status. Neurologic symptom management consists of using dexamethasone and antiepileptic medications. Treatment consists of a combination of surgical and radiation therapy. Surgical treatment is indicated where there is a need for tissue diagnosis or immediate alleviation of neurologic symptoms and mass effect. Stereotactic radiosurgery has become an effective treatment modality. Whole-brain radiation therapy may have a role as an adjunctive therapy. © 2020 Elsevier Inc.

引用

页码：489 / 503

页数：15

共 60 条

[1] The evaluation of MRI diffusion values of active demyelinating lesions in multiple sclerosis [J].

Abdoli, Mohammad ;

Chakraborty, Santanu ;

MacLean, Heather J. ;

Freedman, Mark S. .

MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2016, 10 :97-102

[2] Risk for leptomeningeal seeding after resection for brain metastases: implication of tumor location with mode of resection [J].

Ahn, Jun Hyong ;

Lee, Sang Hyun ;

Kim, Sohee ;

Joo, Jungnam ;

Yoo, Heon ;

Lee, Seung Hoon ;

Shin, Sang Hoon ;

Gwak, Ho-Shin .

JOURNAL OF NEUROSURGERY, 2012, 116 (05) :984-993

[3] Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial [J].

Andrews, DW ;

Scott, CB ;

Sperduto, PW ;

Flanders, AE ;

Gaspar, LE ;

Schell, MC ;

Werner-Wasik, M ;

Demas, W ;

Ryu, J ;

Bahary, JP ;

Souhami, L ;

Rotman, M ;

Mehta, MP ;

Curran, WJ .

LANCET, 2004, 363 (9422) :1665-1672

[4] Impact of 2-staged stereotactic radiosurgery for treatment of brain metastases ≥ 2 cm [J].

Angelov, Lilyana ;

Mohammadi, Alireza M. ;

Bennett, Elizabeth E. ;

Abbassy, Mahmoud ;

Elson, Paul ;

Chao, Samuel T. ;

Montgomery, Joshua S. ;

Habboub, Ghaith ;

Vogelbaum, Michael A. ;

Suh, John H. ;

Murphy, Erin S. ;

Ahluwalia, Manmeet S. ;

Nagel, Sean J. ;

Barnett, Gene H. .

JOURNAL OF NEUROSURGERY, 2018, 129 (02) :366-382

[5] Hypofractionated stereotactic radiotherapy alone without whole-brain irradiation for patients with solitary and oligo brain metastasis using noninvasive fixation of the skull [J].

Aoyama, HI ;

Shirato, H ;

Onimaru, R ;

Kagei, K ;

Ikeda, J ;

Ishii, N ;

Sawamura, Y ;

Miyasaka, K .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 56 (03) :793-800

[6] Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases - A randomized controlled trial [J].

Aoyama, Hidefumi ;

Shirato, Hiroki ;

Tago, Masao ;

Nakagawa, Keiichi ;

Toyoda, Tatsuya ;

Hatano, Kazuo ;

Kenjyo, Masahiro ;

Oya, Natsuo ;

Hirota, Saeko ;

Shioura, Hiroki ;

Kunieda, Etsuo ;

Inomata, Taisuke ;

Hayakawa, Kazushige ;

Katoh, Norio ;

Kobashi, Gen .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 295 (21) :2483-2491

[7] A New Treatment Paradigm: Neoadjuvant Radiosurgery Before Surgical Resection of Brain Metastases With Analysis of Local Tumor Recurrence [J].

Asher, Anthony L. ;

Burri, Stuart H. ;

Wiggins, Walter F. ;

Kelly, Renee P. ;

Boltes, Margaret O. ;

Mehrlich, Melissa ;

Norton, H. James ;

Fraser, Robert W. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 88 (04) :899-906

[8] A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis [J].

Auchter, RM ;

Lamond, JP ;

Alexander, E ;

Buatti, JM ;

Chappell, R ;

Friedman, WA ;

Kinsella, TJ ;

Levin, AB ;

Noyes, WR ;

Schultz, CJ ;

Loeffler, JS ;

Mehta, MP .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1996, 35 (01) :27-35

[9] Metastasis in Adult Brain Tumors [J].

Barajas, Ramon Francisco, Jr. ;

Cha, Soonmee .

NEUROIMAGING CLINICS OF NORTH AMERICA, 2016, 26 (04) :601-+

[10]

Barajas RF, 2012, PROG NEUROL SURG, V25, P55, DOI 10.1159/000331174

← 1 2 3 4 5 6 →