Palladium-Catalyzed Mono-α-Arylation of Acetone with Aryl Imidazolylsulfonates

被引：60

作者：

Ackermann, Lutz ^{[1
]}

Mehta, Vaibhav P. ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2012年 / 18卷 / 33期

关键词：

arylation; C?H activation; C?O activation; imidazolylsulfonate; palladium; phosphane ligands; H BOND ACTIVATION; FORMING REDUCTIVE ELIMINATION; CROSS-COUPLING REACTIONS; C-O BONDS; C(SP(3))-H BONDS; SUZUKI-MIYAURA; KETONES; FUNCTIONALIZATION; CHLOROARENES; TOSYLATES;

D O I：

10.1002/chem.201201394

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Set the ace(tone): A palladium catalyst derived from the bidentate XantPhos ligand and Pd(OAc) 2 has enabled broadly applicable mono-α-arylations of acetone to be performed with air- and moisture-stable aryl imidazolylsulfonates as most user-friendly electrophiles (see scheme). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：10230 / 10233

页数：4

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