Copper-catalyzed synthesis of trifluoromethyl-substituted isoxazolines

被引：136

作者：

He, Yu-Tao ^{[1
]}

Li, Lian-Hua ^{[1
]}

Yang, Yan-Fang ^{[1
]}

Wang, Yu-Qi ^{[1
]}

Luo, Jian-Yi ^{[1
]}

Liu, Xue-Yuan ^{[1
]}

Liang, Yong-Min ^{[1
]}

机构：

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 50期

基金：

美国国家科学基金会;

关键词：

PD(II)-CATALYZED ORTHO-TRIFLUOROMETHYLATION; ARYL BORONIC ACIDS; OXIDATIVE TRIFLUOROMETHYLATION; BOND-FORMATION; NUCLEOPHILIC TRIFLUOROMETHYLATION; MEDIATED TRIFLUOROMETHYLATION; REDUCTIVE ELIMINATION; TRANSITION-METAL; ARENES; ALKENES;

D O I：

10.1039/c3cc42588f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A mild and efficient copper-catalyzed trifluoromethylation reaction which involves the cyclization of oximes has been developed. This method provides a convenient access to a variety of useful CF3-containing 4,5-dihydroisoxazoles by constructing a C-CF3 bond and a C-O bond in one step.

引用

页码：5687 / 5689

页数：3

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