Lateral flow (immuno) assay: its strengths, weaknesses, opportunities and threats. A literature survey

被引:1132
作者
Posthuma-Trumpie, Geertruida A. [2 ]
Korf, Jakob [2 ]
van Amerongen, Aart [1 ]
机构
[1] Univ Wageningen & Res Ctr, Agrotechnol & Food Sci Grp, NL-6700 AA Wageningen, Netherlands
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Psychiat, NL-9700 RB Groningen, Netherlands
关键词
Biomonitoring; Clinical chemistry; Foodsafety; Forensics; Lateral flow assay; Phytopathology; Veterinary; COMPETITIVE IMMUNOCHROMATOGRAPHIC ASSAY; IMMUNOGLOBULIN-M ANTIBODIES; LINKED-IMMUNOSORBENT-ASSAY; DIPSTICK DYE IMMUNOASSAY; DRY REAGENT IMMUNOASSAY; COMPUTER IMAGE-ANALYSIS; FUNGAL ALPHA-AMYLASE; STEP STRIP TEST; RAPID DETECTION; QUANTITATIVE DETECTION;
D O I
10.1007/s00216-008-2287-2
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Lateral flow (immuno) assays are currently used for qualitative, semiquantitative and to some extent quantitative monitoring in resource-poor or non-laboratory environments. Applications include tests on pathogens, drugs, hormones and metabolites in biomedical, phytosanitary, veterinary, feed/food and environmental settings. We describe principles of current formats, applications, limitations and perspectives for quantitative monitoring. We illustrate the potentials and limitations of analysis with lateral flow (immuno) assays using a literature survey and a SWOT analysis (acronym for "strengths, weaknesses, opportunities, threats"). Articles referred to in this survey were searched for on MEDLINE, Scopus and in references of reviewed papers. Search terms included "immunochromatography", "sol particle immunoassay", "lateral flow immunoassay" and "dipstick assay".
引用
收藏
页码:569 / 582
页数:14
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