Lipases as practical biocatalysts

被引：459
作者：
Reetz, MT [1 ]
机构：
[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 02期
关键词：
D O I：
10.1016/S1367-5931(02)00297-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Lipases are the most used enzymes in synthetic organic chemistry, catalyzing the hydrolysis of carboxylic acid esters in aqueous medium or the reverse reaction in organic solvents. Recent methodological advancements regarding practical factors affecting lipase activity and enantioselectivity are reviewed. Select practical examples concerning the use of lipases in the production of chiral intermediates are also highlighted.
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收藏
页码：145 / 150
页数：6
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