Increased serum malondialdehyde and decreased nitric oxide within 24 hours of thrombotic stroke onset

被引：0

作者：

Cano, C ^{[1
]}

Bermúdez, V ^{[1
]}

Atencio, HE ^{[1
]}

Medina, MT ^{[1
]}

Amell, A ^{[1
]}

Souki, A ^{[1
]}

Molina, OM ^{[1
]}

Restrepo, H ^{[1
]}

Vargas, ME ^{[1
]}

Núñez, M ^{[1
]}

Souki, A ^{[1
]}

Vargas, ME ^{[1
]}

Ambard, M ^{[1
]}

Toledo, A ^{[1
]}

Cabrera, JC ^{[1
]}

Ospino, N ^{[1
]}

Fouillioux, C ^{[1
]}

Bolívar, A ^{[1
]}

Contreras, F ^{[1
]}

Velasco, M ^{[1
]}

机构：

[1] Univ Zulia, Ctr Endocrine Metab Res Dr Felix Gomez, Maracaibo 4011, Venezuela

来源：

ADVANCES IN CORONARY ARTERY DISEASE | 2001年

关键词：

stroke; nitric oxide; malondialdehyde; ischemia; reperfusion;

D O I：

暂无

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Ischaemia/reperfusion generates free oxygen radicals, that react with the unsaturated lipids of biomembranes resulting in the generation products such as malondialdehyde (MDA). MDA could be a sensor for tissue damage and reperfusion. Nitric oxide (NO), released due to the early arrival of leukocytes in the brain parenchyma, could be a sensor for non-flow phenomenon. Thereby, the purpose of this research was to evaluate the behavior of MDA and NO within the 24 hours after the stroke onset.

引用

页码：163 / 167

页数：5

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