Iron-Catalyzed Tandem One-Pot Addition and Cyclization of the Blaise Reaction Intermediate and Nitroolefins: Synthesis of Substituted NH-Pyrroles from Nitriles

被引：36

作者：

Zhao, Mi-Na ^{[1
]}

Liang, Hao ^{[1
]}

Ren, Zhi-Hui ^{[1
]}

Guan, Zheng-Hui ^{[1
]}

机构：

[1] NW Univ Xian, Dept Chem & Mat Sci, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2013年 / 355卷 / 01期

基金：

中国国家自然科学基金;

关键词：

addition and cyclization; iron catalysis; nitroolefins; pyrroles; tandem reaction; POLYSUBSTITUTED PYRROLES; MULTISUBSTITUTED PYRROLES; NITROALKENES; DERIVATIVES; ALDEHYDES; ESTERS; ENAMINOESTERS; INHIBITORS; POLYMERS; KETONES;

D O I：

10.1002/adsc.201200673

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The iron-catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH-pyrroles in a tandem one-pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH-pyrroles in good yields.

引用

页码：221 / 226

页数：6

共 43 条

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