Iron-Catalyzed Tandem One-Pot Addition and Cyclization of the Blaise Reaction Intermediate and Nitroolefins: Synthesis of Substituted NH-Pyrroles from Nitriles

被引：36
|
作者：
Zhao, Mi-Na [1 ]
Liang, Hao [1 ]
Ren, Zhi-Hui [1 ]
Guan, Zheng-Hui [1 ]
机构：
[1] NW Univ Xian, Dept Chem & Mat Sci, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2013年 / 355卷 / 01期
基金：
中国国家自然科学基金;
关键词：
addition and cyclization; iron catalysis; nitroolefins; pyrroles; tandem reaction; POLYSUBSTITUTED PYRROLES; MULTISUBSTITUTED PYRROLES; NITROALKENES; DERIVATIVES; ALDEHYDES; ESTERS; ENAMINOESTERS; INHIBITORS; POLYMERS; KETONES;
D O I：
10.1002/adsc.201200673
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The iron-catalyzed addition and cyclization of the Blaise reaction intermediate and nitroolefins to synthesize highly functionalized NH-pyrroles in a tandem one-pot manner from nitriles has been developed. This reaction shows good functional group tolerance and affords a broad spectrum of substituted NH-pyrroles in good yields.
引用
收藏
页码：221 / 226
页数：6
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