INTERSTITIAL MAGNETIC RESONANCE LYMPHOGRAPHY: THE CLINICAL EFFECTIVENESS OF A NEW METHOD

被引:0
作者
Dimakakos, E. [1 ]
Koureas, A. [2 ]
Koutoulidis, V. [2 ]
Skiadas, V. [2 ]
Katsenis, K. [1 ]
Arkadopoulos, N. [1 ]
Gouliamos, A. [3 ]
Vlachos, L. [2 ]
机构
[1] Univ Athens, Surg Clin 2, Vasc Unit, Athens, Greece
[2] Areteio Univ Hosp, Dept Radiol A, Athens, Greece
[3] Attiko Univ Hosp, Dept Radiol B, Athens, Greece
关键词
interstitial magnetic resonance lymphography; gadobutrol; lymphedema; lymphography;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The aim of this study is to evaluate effectiveness of interstitial magnetic resonance lymphography as an examination for the depiction of the lymphatic system in humans by comparison with direct x-ray lymphography. We studied 14 subjects (two volunteers and 12 patients with clinical suspicion of lymphedema of the lower extremities). We first administered subcutaneous gadobutrol between the toes and performed MR lymphography. After seven days, we injected lipiodol into the lymph vessels of 8 patients and performed x-ray direct lymphography to compare findings of two methods. We identified the normal lymphatic system (lymph vessels and inguinal lymph nodes) of volunteers. In seven subjects, we were able to image an abnormal lymphatic system with decreased number of lymph vessels, lymphoceles, and ectatic lymph vessels. In three subjects we identified both an abnormal lymphatic and venous system and in two patients only the venous system. In all cases x-ray direct lymphography confirmed the findings of the MR lymphography. No side effects were observed from either contrast agent. We expect that in the future, interstitial MR lymphography will be improved and evolve into a valuable diagnostic tool for the evaluation of lymphatic diseases particularly those who present with primarily lymphedema in the lower limbs or second, in regions other than extremities.
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页码:116 / 125
页数:10
相关论文
共 24 条
[1]   INITIAL CLINICAL-EXPERIENCE WITH DEXTRAN-COATED SUPERPARAMAGNETIC IRON-OXIDE FOR DETECTION OF LYMPH-NODE METASTASES IN PATIENTS WITH HEAD AND NECK-CANCER [J].
ANZAI, Y ;
BLACKWELL, KE ;
HIRSCHOWITZ, SL ;
ROGERS, JW ;
SATO, Y ;
YUH, WTC ;
RUNGE, VM ;
MORRIS, MR ;
MCLACHLAN, SJ ;
LUFKIN, RB .
RADIOLOGY, 1994, 192 (03) :709-715
[2]   BIODISTRIBUTION OF AN ULTRASMALL SUPERPARAMAGNETIC IRON-OXIDE COLLOID, BMS-180549, BY DIFFERENT ROUTES OF ADMINISTRATION [J].
BENGELE, HH ;
PALMACCI, S ;
ROGERS, J ;
JUNG, CW ;
CRENSHAW, J ;
JOSEPHSON, L .
MAGNETIC RESONANCE IMAGING, 1994, 12 (03) :433-442
[3]  
Dimakakos E, 2006, LYMPHOLOGY, V39, P164
[4]   Interstitial magnetic resonance lymphography with gadobutrol in rats - Evaluation of contrast kinetics [J].
Fink, C ;
Bock, M ;
Kiessling, F ;
Delorme, S .
INVESTIGATIVE RADIOLOGY, 2002, 37 (12) :655-662
[5]  
Fobbe F, 1996, EUR RADIOL, V6, P224
[6]  
FOELDI M, 2003, TXB LYMPHOLOGY, P251
[7]  
FOELDI M, 2003, TXB LYMPHOLOGY, P253
[8]  
FOELDI M, 2003, TXB LYMPHOLOGY, P448
[9]   Encapsulation of Gadobutrol in AVE-based liposomal carriers for MR detectability [J].
Heverhagen, JT ;
Graser, A ;
Fahr, A ;
Müller, R ;
Alfke, H .
MAGNETIC RESONANCE IMAGING, 2004, 22 (04) :483-487
[10]  
Int Soc Lymphology, 2003, LYMPHOLOGY, V36, P84