Chemoselective Hydrogenation of Alkynes to (Z)-Alkenes Using an Air-Stable Base Metal Catalyst

被引：34

作者：

Zubar, Viktoriia ^{[1
,2
]}

Sklyaruk, Jan ^{[2
]}

Brzozowska, Aleksandra ^{[2
]}

Rueping, Magnus ^{[1
]}

机构：

[1] KAUST, KAUST Catalysis Ctr KCC, Thuwal 239556900, Saudi Arabia

[2] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

ORGANIC LETTERS | 2020年 / 22卷 / 14期

关键词：

HOMOGENEOUS HYDROGENATION; SELECTIVE HYDROGENATION; MANGANESE COMPLEXES; SEMIHYDROGENATION; LIGANDS; ACTIVATION; EFFICIENT; KETONES; BOND; PD;

D O I：

10.1021/acs.orglett.0c01783

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective hydrogenation of alkynes using an air-stable and readily available manganese catalyst has been achieved. The reaction proceeds under mild reaction conditions and tolerates various functional groups, resulting in (Z)-alkenes and allylic alcohols in high yields. Mechanistic experiments suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperativity.

引用

页码：5423 / 5428

页数：6

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