New Approaches to Nitrogen Containing Heterocycles: Enantioselective Organocatalyzed Synthesis of Dihydropyridines (DHP's), Quinolizidine Derivatives and Dihydropyrimidines (DHPM's)

被引：0

作者：

Hoai Thu Pham ^{[1
]}

Chataigner, Isabelle ^{[2
]}

Renaud, Jean-Luc ^{[1
]}

机构：

[1] Univ Caen ENSICAEN, UMR CNRS LCMT 6507, F-14050 Caen, France

[2] Univ Rouen, UMR CNRS COBRA 6014, F-76821 Mont St Aignan, France

来源：

CURRENT ORGANIC CHEMISTRY | 2012年 / 16卷 / 15期

关键词：

Dihydropyridines; Dihydropyrimidines; Quinolizidines; Chiral Bronsted acids; Chiral thioureas; Proline type derivatives; CALCIUM-CHANNEL BLOCKERS; SOLVENT-FREE CONDITIONS; BETA-ENAMINO ESTERS; ONE-POT SYNTHESIS; BIGINELLI REACTION; BRONSTED ACID; ASYMMETRIC-SYNTHESIS; MICHAEL ADDITION; PICTET-SPENGLER; ALPHA; BETA-UNSATURATED ALDEHYDES;

D O I：

10.2174/138527212802651322

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitrogen-containing heterocycles, and more specifically the chiral ones, possess various biological and pharmaceutical properties. Among the approaches to these compounds, the organocatalyzed asymmetric multicomponent reaction has emerged as a powerful tool. This review will focus on the later development to chiral dihydropyridines, dihydropyrimidines and quinolizidines via asymmetric organocatalyzed synthesis.

引用

页码：1754 / 1775

页数：22

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