Palladium-Catalyzed Reduction of Acid Chlorides to Aldehydes with Hydrosilanes

被引：16
|
作者：
Fujihara, Tetsuaki [1 ]
Cong, Cong [1 ]
Iwai, Tomohiro [1 ]
Terao, Jun [1 ]
Tsuji, Yasushi [1 ]
机构：
[1] Kyoto Univ, Grad Sch Engn, Dept Energy & Hydrocarbon Chem, Nishikyo Ku, Kyoto 6158510, Japan
来源：
SYNLETT | 2012年 / 16期
关键词：
acid chloride; aldehyde; hydrosilane; palladium; phosphine; TRI-TERT-BUTOXYALUMINOHYDRIDE; ACYL CHLORIDES; ORGANOSILICON HYDRIDES; SODIUM-BOROHYDRIDE; RHODIUM COMPLEXES; TERMINAL ALKYNES; CONVERSION; HYDROSILYLATION; PLATINUM; HALIDES;
D O I：
10.1055/s-0032-1317155
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of aldehydes from acid chlorides with hydrosilanes as a reducing agent in the presence of a palladium catalyst has been achieved. A simple mixture of commercially available Pd(dba)(2) and Mes(3)P as a catalyst realized the reduction of various acid chlorides including aliphatic acid chlorides and alpha,beta-unsaturated acid chlorides to the corresponding aldehydes in good to high yields under mild reaction conditions.
引用
收藏
页码：2389 / 2392
页数：4
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