Radially polarized tip-enhanced near-field coherent anti-Stokes Raman scattering microscopy for bioimaging

被引：1

作者：

Lin, Jian ^{[1
]}

Er, Kenneth ^{[1
]}

Huang, Zhiwei ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Bioengn, Fac Engn, Opt Bioimaging Lab, Singapore 117576, Singapore

来源：

NANOSCALE IMAGING, SENSING, AND ACTUATION FOR BIOMEDICAL APPLICATIONS VIII | 2012年 / 8231卷

关键词：

nonlinear optical microscopy; coherent anti-Stokes Raman scattering; near-field; radial polarization; tip-enhanced; CARS MICROSCOPY; LIGHT; LIMIT;

D O I：

10.1117/12.908476

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

CARS is meritorious in its ability to perform chemical selective imaging, but its spatial resolution is limited by the diffraction limit of light; however, this limit can be broken by combining CARS and near-field scanning microscope. In this work, we report a novel radially polarized near-field coherent anti-Stokes Raman scattering microscopy (RP-NF-CARS), which uses radially polarized light as excitation to enhance the electric field enhancement under a metallic tip, and improves the signal to background ratio compared with that using linearly polarized excitations. We applied RP-NF-CARS to image nano-scale polystyrene beads and biological system.

引用

页数：6

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