A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell

被引：326
作者：
Cheng, Tanyu [1 ]
Xu, Yuifang [1 ]
Zhang, Shenyi [1 ]
Zhu, Weiping [1 ]
Qian, Xuhong [1 ]
Duan, Liping [1 ]
机构：
[1] E China Univ Sci & Technol, Sch Pharm, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 48期
基金：
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词：
D O I：
10.1021/ja806928n
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly selective and sensitive OFF-ON fluorescent sensor 1, employing the PET mechanism, was designed and synthesized. It could be used to detect Cd2+ ion in aqueous solution and to image Cd2+ ion in living cells. The fluorescence intensity significantly enhanced about 195-fold and the quantum yield increased almost 100-fold. Moreover the fluorescence intensity of 1 increased linearly with high sensitivity (0-1 mu M) toward Cd2+.
引用
收藏
页码：16160 / +
页数：3
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