A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell

被引：326

作者：

Cheng, Tanyu ^{[1
]}

Xu, Yuifang ^{[1
]}

Zhang, Shenyi ^{[1
]}

Zhu, Weiping ^{[1
]}

Qian, Xuhong ^{[1
]}

Duan, Liping ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Sch Pharm, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 48期

基金：

中国国家自然科学基金; 国家高技术研究发展计划(863计划);

关键词：

D O I：

10.1021/ja806928n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly selective and sensitive OFF-ON fluorescent sensor 1, employing the PET mechanism, was designed and synthesized. It could be used to detect Cd2+ ion in aqueous solution and to image Cd2+ ion in living cells. The fluorescence intensity significantly enhanced about 195-fold and the quantum yield increased almost 100-fold. Moreover the fluorescence intensity of 1 increased linearly with high sensitivity (0-1 mu M) toward Cd2+.

引用

页码：16160 / +

页数：3

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