Peripheral Artery Disease and Aortic Disease

被引:7
作者
Criqui, Michael H. [1 ,2 ]
Aboyans, Victor [3 ,4 ]
Allison, Matthew A. [1 ]
Denenberg, Julie O. [1 ]
Forbang, Nketi [1 ]
McDermott, Mary M. [5 ,6 ]
Wassel, Christina L. [7 ]
Wong, Nathan D. [8 ]
机构
[1] Univ Calif San Diego, Dept Family Med & Publ Hlth, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
[3] Dupuytren Univ Hosp, Dept Cardiol, Limoges, France
[4] Univ Limoges, Trop Neuroepidemiol, Inserm 1094, Limoges, France
[5] Northwestern Univ, Dept Med, Feinberg Sch Med, Chicago, IL 60611 USA
[6] Northwestern Univ, Dept Prevent Med, Feinberg Sch Med, Chicago, IL 60611 USA
[7] Univ Vermont, Dept Pathol & Lab Med, Coll Med, Burlington, VT 05405 USA
[8] Univ Calif Irvine, Div Cardiol, Heart Dis Prevent Program, Irvine, CA USA
关键词
ANKLE-BRACHIAL INDEX; GENOME-WIDE ASSOCIATION; BONE-MINERAL DENSITY; SUBCLINICAL CARDIOVASCULAR-DISEASE; CORONARY-HEART-DISEASE; RISK-FACTORS; CHROMOSOME; 9P21; CALCIFIED ATHEROSCLEROSIS; INSULIN-RESPONSE; ABDOMINAL-AORTA;
D O I
10.1016/j.gheart.2016.08.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We reviewed published MESA (Multi-Ethnic Study of Atherosclerosis) study articles concerning peripheral arterial disease, subclavian stenosis (SS), abdominal aortic calcium (AAC), and thoracic artery calcium (TAC). Important findings include, compared to non-Hispanic whites, lower ankle-brachial index (ABI) and more SS in African Americans, and higher ABI and less SS in Hispanic and Chinese Americans. Abnormal ABI and brachial pressure differences were associated with other subclinical cardiovascular disease (CVD) measures. Both very high and low ABI independently predicted increased CVD events. Looking at aortic measures, TAC and AAC were significantly associated with other subclinical CVD measures. Comparisons of AAC with coronary artery calcium (CAC) showed that both were less common in ethnic minority groups. However, although CAC was much more common in men than in women in multivariable analysis, this was not true of AAC. Also, when AAC and CAC were adjusted for each other in multivariable analysis, there was a stronger association for AAC than for CAC with CVD and total mortality.
引用
收藏
页码:313 / 326
页数:14
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