Clinical utility of heart rate variability during Head-up tilt test in subjects with chronic posttraumatic stress disorder

被引：2

作者：

Park, Joo Eon ^{[1
]}

Kang, Suk-Hoon ^{[2
,3
,4
]}

Lee, Ji Yeon ^{[5
]}

Won, Sung-Doo ^{[6
]}

So, Hyung Seok ^{[3
]}

Choi, Jin Hee ^{[3
]}

Kim, Chan-Hyung ^{[2
]}

Yoon, In Young ^{[2
,7
]}

机构：

[1] Keyo Hosp, Dept Psychiat, Uiwang, South Korea

[2] Yonsei Univ, Dept Psychiat, Coll Med, Grad Sch, Seoul, South Korea

[3] Vet Hlth Serv Med Ctr, Dept Psychiat, Seoul, South Korea

[4] Vet Hlth Serv Med Ctr, Ctr Sleep Med, Seoul, South Korea

[5] SMG SNU Boramae Med Ctr, Dept Psychiat, Seoul, South Korea

[6] Keyo Hosp, Clin Psychol, Uiwang, South Korea

[7] Seoul Natl Univ, Dept Neuropsychiat, Bundang Hosp, Seongnam Si, Gyeonggi Do, South Korea

来源：

PSYCHIATRY RESEARCH | 2019年 / 272卷

关键词：

Posttraumatic stress disorder; Heart rate variability; Head-up tilt test; Autonomic dysfunction; TRAUMA; MODULATION; METAANALYSIS; POWER;

D O I：

10.1016/j.psychres.2018.12.035

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Posttraumatic stress disorder (PTSD) is characterized by psychophysiological abnormalities, such as an altered baseline heart rate and hyperarousal, implying dysfunctional arousal regulation. Heart rate variabilities (HRVs) is known to reflect autonomic nervous system activity. We examined the changes of HRVs in PTSD patients with head-up tilt position to closely investigate disease-specific changes in autonomic function in PTSD patients. Sixty-seven patients with PTSD and 72 patients without PTSD were assessed using the PTSD Checklist for DSM-5 (PCL-5) and psychiatric interview. Heart rate data including standard deviation of the NN intervals, the square root of the mean squared differences of successive NN intervals, log low-frequency and log high-frequency were collected for 10 min before and after tilting. Considering interactions between groups and head-up tilting, the head-up tilting induced reduction of the high-frequency component of HRVs was significantly greater in the PTSD group [F (1, 272) = 4.718, p = 0.031]. The change of HRVs in PTSD patients suggested the presence of autonomic dysfunction in despite of the posture.

引用

页码：100 / 105

页数：6