Intermolecular Anodic Oxidative Cross-Dehydrogenative C(sp3)-N Bond-Coupling Reactions of Xanthenes with Azoles

被引：90

作者：

Yang, Yong-Zheng ^{[1
]}

Song, Ren-Jie ^{[1
]}

Li, Jin-Heng ^{[1
,2
]}

机构：

[1] Nanchang Hangkong Univ, Key Lab Jiangxi Prov Persistent Pollutants Contro, Nanchang 330063, Jiangxi, Peoples R China

[2] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

ORGANIC LETTERS | 2019年 / 21卷 / 09期

关键词：

C-H AMIDATION; BASE-FREE; FUNCTIONALIZATION; DERIVATIVES; AMINATION; STRATEGY; PHOSPHORYLATION; ACTIVATION; ETHERS;

D O I：

10.1021/acs.orglett.9b00947

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new anode strategy for accessing xanthen-9-azoles via an electrochemical C(sp(3))-H/N-H cross-coupling of xanthenes with azoles is described. This reaction proceeds efficiently with a broad scope of both xanthenes and N-H-free azoles under metal- and additional oxidant-free conditions and represents a new access to direct incorporation of important N-heterocycle units into the resulting xanthenes.

引用

页码：3228 / 3231

页数：4

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