Can a Two-Faced Kinase be Exploited for Osteosarcoma?

被引：8
作者：
Woodgett, James R. [1 ,2 ]
机构：
[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada
[2] Univ Toronto, Dept Med Biophys, Toronto, ON, Canada
来源：
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE | 2012年 / 104卷 / 10期
关键词：
NF-KAPPA-B; PROTEIN-KINASE; 3-BETA;
D O I：
10.1093/jnci/djs223
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：722 / 723
页数：2
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共 13 条
  • [1] EMBRYONIC LETHALITY AND LIVER DEGENERATION IN MICE LACKING THE RELA COMPONENT OF NF-KAPPA-B
    BEG, AA
    SHA, WC
    BRONSON, RT
    GHOSH, S
    BALTIMORE, D
    [J]. NATURE, 1995, 376 (6536) : 167 - 170
  • [2] NF-κB and the link between inflammation and cancer
    DiDonato, Joseph A.
    Mercurio, Frank
    Karin, Michael
    [J]. IMMUNOLOGICAL REVIEWS, 2012, 246 : 379 - 400
  • [3] Differential regulation of glycogen synthase kinase 3β by insulin and Wnt signaling
    Ding, VW
    Chen, RH
    McCormick, F
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (42) : 32475 - 32481
  • [4] Functional redundancy of GSK-3α and GSK-3β in Wnt/β-catenin signaling shown by using an allelic series of embryonic stem cell lines
    Doble, Bradley W.
    Patel, Satish
    Wood, Geoffrey A.
    Kockeritz, Lisa K.
    Woodgett, James R.
    [J]. DEVELOPMENTAL CELL, 2007, 12 (06) : 957 - 971
  • [5] GLYCOGEN-SYNTHASE KINASE-3 FROM RABBIT SKELETAL-MUSCLE - SEPARATION FROM CYCLIC-AMP-DEPENDENT PROTEIN-KINASE AND PHOSPHORYLASE-KINASE
    EMBI, N
    RYLATT, DB
    COHEN, P
    [J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1980, 107 (02): : 519 - 527
  • [6] Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-β-catenin pathway
    Hoang, BH
    Kubo, T
    Healey, JH
    Yang, R
    Nathan, SS
    Kolb, EA
    Mazza, B
    Meyers, PA
    Gorlick, R
    [J]. CANCER RESEARCH, 2004, 64 (08) : 2734 - 2739
  • [7] Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
    Hoeflich, KP
    Luo, J
    Rubie, EA
    Tsao, MS
    Jin, O
    Woodgett, JR
    [J]. NATURE, 2000, 406 (6791) : 86 - 90
  • [8] Glycogen synthase kinase 3α-specific regulation of murine hepatic glycogen metabolism
    MacAulay, Katrina
    Doble, Bradley W.
    Patel, Satish
    Hansotia, Tanya
    Sinclair, Elaine M.
    Drucker, Daniel J.
    Nagy, Andras
    Woodgett, James R.
    [J]. CELL METABOLISM, 2007, 6 (04) : 329 - 337
  • [9] The protein kinase complement of the human genome
    Manning, G
    Whyte, DB
    Martinez, R
    Hunter, T
    Sudarsanam, S
    [J]. SCIENCE, 2002, 298 (5600) : 1912 - +
  • [10] When pathways collide: collaboration and connivance among signalling proteins in development
    McNeill, Helen
    Woodgett, James R.
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2010, 11 (06) : 404 - 413
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