Thiourea dioxide catalyzed multi-component coupling reaction for the one step synthesis of naphthopyran derivatives

被引：41
作者：
Verma, Sanny [1 ]
Jain, Suman L. [1 ]
机构：
[1] CSIR Indian Inst Petr, Div Chem Sci, Dehra Dun 248005, Uttar Pradesh, India
来源：
TETRAHEDRON LETTERS | 2012年 / 53卷 / 45期
关键词：
Naphthopyran; Multicomponent coupling; Thiourea dioxide; Organocatalyst; ONE-POT SYNTHESIS; BASIC IONIC LIQUID; ASYMMETRIC ORGANOCATALYSIS; RECYCLABLE CATALYST; DOMINO; ACID;
D O I：
10.1016/j.tetlet.2012.08.118
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An aqueous solution of thiourea dioxide was used to catalyze a one-pot three-component coupling reaction of an aromatic aldehyde, malononitrile, and alpha- or beta-naphthol for the synthesis of various naphthopyran derivatives in excellent yields. At the end of the reaction, the product was isolated by filtration or extraction and the remaining aqueous solution of thiourea dioxide was reused as such for several subsequent runs. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6055 / 6058
页数：4
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