Healthcare utilisation and costs in the diagnosis and treatment of progressive-fibrosing interstitial lung diseases

被引:23
作者
Holtze, Colin [1 ]
Flaherty, Kevin [1 ]
Kreuter, Michael [2 ,3 ]
Luppi, Fabrizio [4 ]
Moua, Teng [5 ]
Vancheri, Carlo [6 ]
Scholand, Mary B. [7 ]
机构
[1] Univ Michigan, Div Pulm & Crit Carc Med, North Campus Res Complex,Bldg 014-G012, Ann Arbor, MI 48109 USA
[2] Heidelberg Univ, Ctr Interstitial & Rare Lung Dis Pneumol & Resp C, Thoraxklin, Heidelberg, Germany
[3] German Ctr Lung Res, Heidelberg, Germany
[4] Univ Hosp, Ctr Rare Lung Dis, Modena, Italy
[5] Mayo Clin, Div Pulm & Crit Care Med, Rochester, MN USA
[6] Univ Catania, Univ Hosp Policlin Vitt Emanuele, Dept Clin & Expt Med, Catania, Italy
[7] Univ Utah, Sch Med, Dept Internal Med, Salt Lake City, UT USA
关键词
IDIOPATHIC PULMONARY-FIBROSIS; ACUTE EXACERBATION; NINTEDANIB; PIRFENIDONE; CLASSIFICATION; UPDATE;
D O I
10.1183/16000617.0078-2018
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
There are over 200 interstitial lung diseases (ILDs). In addition to patients with idiopathic pulmonary fibrosis (IPF), a percentage of patients with other ILDs also develop progressive fibrosis of the lung during their disease course. Patients with progressive-fibrosing ILDs may show limited response to immunomodulatory therapy, worsening symptoms and lung function and, ultimately, early mortality. There are few data for ILDs that may present a progressive fibrosing phenotype specifically, but we believe the burden and healthcare costs associated with these conditions may be comparable to those reported in IPF. This review discusses the burden of ILDs that may present a progressive fibrosing phenotype and the factors impacting healthcare utilisation.
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页数:6
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