Cutaneous leishmaniasis caused by Leishmania infantum transmitted by Phlebotomus tobbi

被引：133

作者：

Svobodova, Milena ^{[1
]}

Alten, Bulent ^{[2
]}

Zidkova, Lenka ^{[1
]}

Dvorak, Vit ^{[1
]}

Hlavackova, Jitka ^{[1
]}

Myskova, Jitka ^{[1
]}

Seblova, Veronika ^{[1
]}

Kasap, Ozge Erisoz ^{[2
]}

Belen, Asli ^{[2
]}

Votypka, Jan ^{[1
]}

Volf, Petr ^{[1
]}

机构：

[1] Charles Univ Prague, Dept Parasitol, CR-12844 Prague, Czech Republic

[2] Hacettepe Univ, Dept Biol, Fac Sci, TR-06532 Ankara, Turkey

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 2009年 / 39卷 / 02期

关键词：

Cutaneous leishmaniasis; Sand fly; Transmission; Epidemiology; Anthroponosis; Leishmania infantum; Phlebotomus tobbi; SAND FLIES DIPTERA; VISCERAL LEISHMANIASIS; MITOCHONDRIAL-DNA; ABRUZZI REGION; TURKEY; POLYMORPHISM; PSYCHODIDAE; SANDFLIES; AGENT; DIAGNOSIS;

D O I：

10.1016/j.ijpara.2008.06.016

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Transmission of cutaneous leishmaniasis (CL) caused by Leishmania infantum was studied in South Anatolia, Turkey. Small, non-ulcerating lesions prevailed and patients were negative in rK39 tests for antibody detection for human visceral leishmaniasis (VL). The most abundant sand fly species, Phlebotomus tobbi, was found positive for Leishmania promastigotes with a prevalence of 1.4% (13 out of 898 dissected females). The isolated strains were identical with those obtained from patients with CL and were typed as L infantum. Phylogenetic analysis revealed similarity to MON-188 and a clear difference from the MON-1 clade. Blood-meal identification showed that A tobbi feeds preferentially on cattle and humans. This finding, the high number of CL patients and relative scarcity of dogs in the focus, suggests that the transmission cycle could be anthroponotic. (c) 2008 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：251 / 256

页数：6

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